Infectious diseases are a major cause of larval mortality in finfish aquaculture. Understanding ontogeny of the fish immune system and thus developmental timing of protective immune tissues and cells, may help to decrease serious losses of larval fishes when they are particularly vulnerable to infection. One component of the innate immune system of fishes is the host-defense peptides, which include the piscidins. Piscidins are small, amphipathic, α-helical peptides with a broad-spectrum of action against viral, bacterial, fungal, and protozoan pathogens. We describe for the first time the cellular and tissue localization of three different piscidins (1, 3, and 4) during striped bass (Morone saxatilis) larval ontogeny using immunofluorescent histochemistry. From 16 days post hatch to 12 months of age, piscidin staining was observed in cells of the epithelial tissues of gill, digestive tract, and skin, mainly in mast cells. Staining was also seen in presumptive hematopoietic cells in the head kidney. The three piscidins showed variable cellular and tissue staining patterns, possibly relating to differences in tissue susceptibility or pathogen specificity. This furthers our observation that the piscidins are not a monolithic family of antimicrobials, but that different AMPs have different (more specialized) functions. Furthermore, no immunofluorescent staining of piscidins was observed in post-vitellogenic oocytes, embryos, or larvae from hatch to 14 days post hatch, indicating that this critical component of the innate immune system is inactive in pre-hatch and young larval striped bass.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.fsi.2016.12.034 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Tracking animal movements via collaborative acoustic telemetry networks: Multiscale habitat use, phenology, and management insights.
J Fish Biol
September 2024
Department of Biological Sciences, University of New Hampshire, Durham, New Hampshire, USA.
Estuaries support diverse fish and invertebrate communities, including resident species that rely on estuarine habitats year-round and transient migratory species. The unique movement patterns of these animals connect habitats within and far beyond the estuary and are integrally linked to fisheries management objectives. With a focus on Chesapeake Bay, this study leveraged data from collaborative acoustic telemetry networks in the northwest Atlantic to assess habitat use and phenology of movements for seven species of fish (cownose rays, dusky sharks, smooth dogfish, alewife, striped bass, common carp, and blue catfish) and one invertebrate (horseshoe crabs).
View Article and Find Full Text PDFApplication potential of albendazole as an aquatic animal drug based on its safety, efficacy, and residue profiles.
Toxicol Res
October 2024
Pesticide and Veterinary Drug Residues Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Osong, Chungcheongbuk-do 28159 Republic of Korea.
Article Synopsis
- The lack of adequate drug options for treating parasites in aquatic animals has led researchers to explore the repurposing of existing livestock drugs, particularly albendazole (ABZ), which has shown effectiveness in various species.* -
- Toxicological studies revealed that ABZ depletes quickly from muscle tissues of several fish but may cause toxicity at high doses, similar to effects seen in humans and other animals.* -
- Efficacy trials demonstrated that ABZ can effectively treat parasites in species like eels and shrimp, making it a potentially valuable alternative for fish farmers facing high demands for new veterinary drugs in aquaculture.*
Development and characterization of primary cell culture from the spinal cord of Asian seabass, Lates calcarifer.
In Vitro Cell Dev Biol Anim
September 2024
Aquatic Animal Health Laboratory, PG & Research Department of Zoology, C. Abdul Hakeem College (Affiliated Thiruvalluvar University), Melvisharam, 632509, Tamil Nadu, India.
Asian seabass, Lates calcarifer, is one of the most important fish species in aquaculture. An attempt was made to develop a primary cell culture from the spinal cord of Lates calcarifer by the enzymatic and mechanical dissociation method. The primary cell culture was sub-cultured for 20 times in Leibovitz's L-15 medium with 20% fetal bovine serum (FBS) and 0.
View Article and Find Full Text PDFCombined screening and retroactive data mining for emerging perfluoroethers in wildlife and pets in the Cape Fear region of North Carolina.
Chemosphere
September 2024
Department of Biological Sciences, North Carolina State University, Raleigh, NC, 27695, USA. Electronic address:
The recent application of non-targeted analysis (NTA) techniques in environmental monitoring has revealed numerous novel fluorinated species in surface water, wildlife, and humans in the Cape Fear River (CFR) region of North Carolina. In this study, we have re-examined archived alligator, striped bass, horse, and dog serum as well as archived seabird tissue data from previously reported exposure studies in order to extend the panel of detected novel PFAS. In this study, the compounds CF-(OCF)-COOH, x = 6, 7, 8 (Abbreviated PFO6TeDA, PFO7HxDA, PFO8OcDA, respectively), and 6H-Perfluoro-3-oxa,4-methylhexanesulfonic acid (Nafion byproduct 6) were detected for the first time in environmental tissues even though these analytes were not previously detected in the CFR.
View Article and Find Full Text PDFNervous necrosis virus capsid protein and Protein A dynamically modulate the fish cGAS-mediated IFN signal pathway to facilitate viral evasion.
J Virol
July 2024
State Key Laboratory of Biocontrol, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), China-ASEAN Belt and Road Joint Laboratory on Mariculture Technology, Guangdong Provincial Key Laboratory of Aquatic Economic Animals, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Nervous necrosis virus (NNV), an aquatic RNA virus belonging to , infects a variety of marine and freshwater fishes, leading to massive mortality of cultured larvae and juveniles and substantial economic losses. The enzyme cyclic guanosine monophosphate-adenosine monophosphate synthase (cGAS) is widely recognized as a central component in the innate immune response to cytosolic DNA derived from different pathogens. However, little is known about the response of cGAS to aquatic RNA viruses.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!