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Effects of low-frequency rTMS combined with antidepressants on depression in patients with post-stroke depression: a systematic review and meta-analysis.
Front Neurol
May 2023
Rehabilitation Department, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Objective: To evaluate the effect of low-frequency (≤1 Hz) repetitive transcranial magnetic stimulation (low-frequency rTMS) combined with antidepressants on depression and the levels of inflammatory factors IL-6 and TNF-α in patients with post-stroke depression (PSD).
Design: PubMed, Embase, Web of Science, Cochrane Library (CBM), China National Knowledge Infrastructure, Technology Periodical Database, and Wanfang Database were searched until October 2022 for randomized controlled trials.
Participants: Patients with post-stroke depression (PSD) participated in the study.
Pediatric Ventilation Skills by Non-Healthcare Students: Effectiveness, Self-Perception, and Preference.
Int J Environ Res Public Health
February 2023
CLINURSID Research Group, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Since a great number of infant cardiopulmonary arrests occur outside of the hospital, it is crucial to train laypersons in cardiopulmonary resuscitation techniques, especially those professionals that will work with infants and children. The main objective of this study was to evaluate the efectiveness of ventilations performed by professional training students. The secondary objective was to analyze the preference between different ventilation and chest-compression methods.
View Article and Find Full Text PDFCost-effectiveness analysis of sintilimab plus pemetrexed and platinum versus chemotherapy alone as first-line treatment in metastatic non-squamous non-small cell lung cancer in China.
Health Econ Rev
December 2022
Department of Medical Insurance, Cancer Prevention and Treatment Institute of Chengdu, Chengdu Fifth People's Hospital (The Second Clinical Medical College, Affiliated Fifth People's Hospital of Chengdu University of Traditional Chinese Medicine), Chengdu, China.
Objective: In frst-line treatment of advanced or metastatic nonsquamous non-small-cell lung cancer (NSCLC), the ORIENT-11 study demonstrated a signifcant progression-free survival and overall survival for sintilimab plus chemotherapy in comparison with chemotherapy alone. But the cost-effectiveness of the two treatment schemes is unclear in China. The objective of the current study was to evaluate the cost efectiveness of sintilimab plus chemotherapy versus Platinum-based chemotherapy for locally advanced or metastatic squamous NSCLC in China.
View Article and Find Full Text PDFIs metformin a geroprotector? A peek into the current clinical and experimental data.
Mech Ageing Dev
October 2020
Laboratory of Bioanalysis, Department of Pharmaceutical Chemistry, Drug Analysis and Radiopharmacy, Medical University of Lodz, ul. Muszyńskiego 1, 90-151 Lodz, Poland. Electronic address:
Nowadays we observe a growing scientific interest and need to develop novel research approach that target ageing. Metformin, apart from its proven efectiveness as a glucose-lowering agent, was found to exert multidirectional effects because of its cardioprotective, anti-inflammatory and anti-cancer activity. Recently, metformin has become a subject of interest of many researchers as a promising drug with anti-ageing properties; however, its impact on clinical ageing features is still hypothetical.
View Article and Find Full Text PDFSoil biotreatment effectiveness for reducing global warming potential from main polluting tillage operations in life cycle assessment phase.
Sci Total Environ
June 2019
Institute of Agricultural Engineering and Safety, Vytautas Magnus University, Lithuania. Electronic address:
In order to reduce global warming potential (GWP) due to anthropogenic and natural factors in the cultivation of winter wheat and rapeseed, proved effectiveness of soil biotreatment with different composition of bio-solutions. It was reduced greenhouse gases (GHG) through life cycle impact categories from the main polluting agricultural operations on deeply lukewarm soaked soil. According to the impact diapason evaluated the main indicators such as human toxicity air (HTA), ecotoxicity water chronic (EWC), global warming potential, ecotoxicity water acute (EWA), ozone formation (OF), human toxicity water (HTW), ecotoxicity soil chronic (ESC), human toxicity soil (HTS), terrestrial eutrophication (TE), acidification (A).
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