Introduction: Development of technologies to reduce transfusion risks of infectious diseases is a major characteristic of hemotherapy. Thus, each donation undergoes clinical and serological screening tests to ensure the donated blood do not offer risks to the receiver.
Objective: Evaluate the prevalence of positive serology in blood donations rejected by Hemobanco (Curitiba - PR) in the period ranging from January 2003 to December 2012.
Methodology: During the period studied, we observed the total number of donations and its division according to gender. We also analyzed the number of rejected donations due to seropositivity, considering the diseases investigated routinely in blood banks in Brazil, and the frequency of discards according to age groups.
Results: Within the period studied, 399,280 donations were performed. 62.0% donors were male. Comparing 2003 to 2012, we noticed a significant decrease of discards, from 10.2% to 5.0%, respectively. There was a reduction of seropositivity for HIV, HBsAg and anti-HBc and an increase for Chagas Disease, hepatitis C, syphilis and HTLV. The age group with the highest prevalence for discards changed: it used to be the 40-59 years old group in 2003, and became the 20-39 years old group in 2012.
Conclusion: There was an increase in the number of donations in Hemobanco and a decrease in total discards due to seropositive donations. Most donors were male. The most prevalent cause of discards only amongst seropositive donation discards is seropositivity for anti-HBc. There was a significant increase of donors aged between 20 and 39 years old.
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http://dx.doi.org/10.1016/j.transci.2016.10.007 | DOI Listing |
Biotechnol Biofuels Bioprod
January 2025
Institute for Pulsed Power and Microwave Technology (IHM), Karlsruhe Institute of Technology (KIT), Eggenstein-Leopoldshafen, Germany.
Background: The gradual extrusion of water-soluble intracellular components (such as proteins) from microalgae after pulsed electric field (PEF) treatment is a well-documented phenomenon. This could be utilized in biorefinery applications with lipid extraction taking place after such an 'incubation' period, i.e.
View Article and Find Full Text PDFBackground: The rising obesity rates in the USA have led to a surge in various weight loss treatments. Glucagon-like peptide-1 (GLP-1) analogues have shown promise in reducing weight but primarily studied in Caucasian populations. Sleeve gastrectomy (SG) has already proven successful weight loss outcomes.
View Article and Find Full Text PDFEur J Clin Microbiol Infect Dis
January 2025
National reference centre for Haemophilus influenzae, Department of microbiology, Laboratoire Hospitalier Universitaire de Bruxelles - Universitair Laboratorium Brussel (LHUB-ULB), Université libre de Bruxelles, Brussels, Belgium.
Introduction: Haemophilus influenzae plays a major role in invasive bacterial infections. Resistant strains are emerging, prompting the WHO to include H. influenzae on its list of priority pathogens for research and development of new antibiotics.
View Article and Find Full Text PDFRev Argent Microbiol
January 2025
Department of Microbiology, School of Medicine and PhD Program in Clinical Medicine and Public Health, University of Granada & Ibs, Granada, Spain; Department of Microbiology, Hospital Virgen de las Nieves, Institute for Biosanitary Research-Ibs, Granada, Spain.
Carbapenemase-producing Enterobacterales (CPE) have increased in the last decade. In low-income countries, colistin is considered a last resort antimicrobial to treat CPE infections, whose most worrisome mechanism of resistance is MCR-1 production. This study aims to understand the epidemiology of colistin resistance in CPE in the region, through the surveillance of the mcr-1 gene in CPE isolates in Ecuador.
View Article and Find Full Text PDFEcotoxicol Environ Saf
January 2025
State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing 210023, China.
The abrasion of melamine cleaning sponges release microplastic fibers (MPFs) into the environment, yet the potential risks remain unknown. Here, we evaluated the ingestion, elimination, and toxic effects of melamine MPFs on Daphnia magna through acute and chronic exposures. This new type of MPFs displayed different morphology (a combination of linear and branched fibers with a length ranging from 10 to 157 μm) from the widely-studied MPFs released from textiles (longer and thicker linear fibers but no branched fibers).
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