AI Article Synopsis

  • The study compared the elasticity patterns of undescended testes and their descended counterparts using shear wave elastography (SWE) in 29 male patients aged 1 to 18 years.
  • It was found that while there was no volume difference between undescended and descended testes, SWE revealed significant variations in elasticity data.
  • The findings suggest that SWE could serve as a predictive tool for histologic characteristics of undescended testes, potentially reducing the need for invasive biopsies.

Article Abstract

Objectives: We sought to compare unilateral palpable undescended testes and contralateral descended testes using shear wave elastography (SWE) to show potential quantitative differences in elasticity patterns, which might reflect the histologic features.

Methods: Approval for this prospective study was obtained from the local ethics committee. A total of 29 patients (mean age, 7.52 years; range, 1-18 years) with unilateral palpable undescended testes and contralateral descended testes were examined by greyscale ultrasonography and SWE between February 2015 and April 2016. The volume and the elasticity of each testicle were the main factors evaluated.

Results: There was no difference between undescended testes and contralateral descended testes in terms of volume. However, a significant difference was evident in SWE-derived quantitative data.

Conclusions: SWE seems to be a useful sonographic technique to predict histologic features of the undescended testicle, which might replace testicular biopsy in modern management of the undescended testis.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejrad.2016.11.026DOI Listing

Publication Analysis

Top Keywords

undescended testes
16
unilateral palpable
12
palpable undescended
12
testes contralateral
12
contralateral descended
12
descended testes
12
shear wave
8
wave elastography
8
testes
7
undescended
6

Similar Publications

Cryptorchidism, the absence of one or both testicles in the scrotum, is the most common anomaly of genitourinary tract in males. The pathogenesis of undescended testes is unknown however the role of inflammation, tissue remodeling and oxidative stress is postulated. The aim of this study was to explore the role of HSP-70, MMP-3, MMP-17 and IL-8 in possible pathogenic pathways connected with cryptorchidism.

View Article and Find Full Text PDF

Cryptorchidism is the most frequent congenital defect in newborn males characterized by the absence of the testis from the scrotum. Approximately 90% of patients with untreated bilateral cryptorchidism exhibit azoospermia due to defective spermatogenesis in the affected testis. While abnormal spermatogonial stem cell maintenance or differentiation is suggested to cause germ cell degeneration in the cryptorchid testis, underlying molecular mechanisms remain unclear.

View Article and Find Full Text PDF

The Role of Laparoscopy in Managing Impalpable Undescended Testes in a Tertiary Hospital.

Mymensingh Med J

January 2025

Dr Mohammad Showkot Ali, Assistant Professor, Department of Pediatric Surgery, Mymensingh Medical College (MMC), Mymensingh, Bangladesh; E-mail:

One of the most prevalent congenital defects in boys is undescended testes. Ultrasound is commonly employed to locate the testis in cases of impalpable testes, which frequently yields false-negative results. Laparoscopy has gained widespread acceptance recently for managing impalpable testes.

View Article and Find Full Text PDF

Platelet-rich plasma effects on in vitro cells derived from pediatric patients with andrological diseases.

Sci Rep

December 2024

Department of Neurosciences, Biomedicine and Movement Sciences, Biochemistry Section, University of Verona, Verona, Italy.

Undescended testis and testicular torsion represent two frequent andrological diseases that affect the pediatric age. Despite these testicular disorders having different causes, they both negatively influence fertility in adulthood mainly due to the accumulation of reactive oxygen species (ROS), which represents the primary molecular damage underlying their long-term effects. The gold standard of treatment for both pathologies is surgery; however, it cannot guarantee an optimal fertility outcome in all clinical cases, underscoring the need to identify effective adjuvant therapies that may target the augmented ROS levels.

View Article and Find Full Text PDF

Introduction: Cryptorchidism impairs sperm development and increases the risk of infertility and testicular cancer. Estrogen signalling is critical for proper descent of the testicles, and hormonal imbalances play a role in cryptorchidism. CYP19, also known as aromatase, encodes an enzyme that converts testosterone, a male sex hormone, into estradiol, the main form of estrogen.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!