Objectives: Early implant failure and donor-site complication remain a concern in patients with thoracolumbar burst fracture underwent one-above and-below short-segment posterior pedicle screw fixation with fusion. Our aim was to evaluate the results of short-segment pedicle instrumentation enforced by two augmenting screws or injectable artificial bone cement in the fractured vertebra, and compare the differences between these two PATIENTS AND METHODS: We conducted a retrospective clinical and radiographic study. Twenty-seven patients were treated with a six-screw construct (group 1), and twenty-nine patients underwenta four-screw construct and fractured vertebra augmentation by injectable calcium sulfate/phosphate cement (group 2). Posterior or posterolateral fusions were not performed in both groups. The severity of the fractured vertebra was evaluated by the load-sharing classification (LSC). Local kyphosis and anterior body height of the fractured vertebra were measured and were follow-up at least 2 years. Any implant failure or loss of correction >10° degrees at the final was defined as failure of surgery. Patients' clinical results were assessed by the Denis scale.
Results: Blood loss and operation time were less in group 1 (126.2±9.7 vs. 267.6±126.1ml, p<0.001 and 141.2±48.7 vs. 189.8±16.4min, p<0.001). Immediately after surgery, group 2 had a better local kyphosis angle (3.7±5.3 vs.6.0±4.1°, p=0.047) and acquired more anterior body height (94.9%±7.6% vs. 84.9%±10.0%, p<0.001). Both groups had similar clinical results (pain score: 1.5±0.8vs. 1.4±0.6, p=0.706; work score: 1.7±0.9 vs. 1.6±1.0, p=0.854). Group 1 had 3 cases of surgery failure; group 2 had 8 cases of implant failure (p=0.121). The average LSC score of these 11 patients with surgical failure was 7.2.
Conclusion: Thesix-screw construct had the advantage of shorter operating time, less blood loss, and lower failure rate. For those patients with anLSC score ≧7, posterior short-segment instrumentation should be used cautiously.
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http://dx.doi.org/10.1016/j.clineuro.2016.12.011 | DOI Listing |
Global Spine J
January 2025
Department of Spinal Surgery, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Study Design: Retrospective Cohort Study.
Objectives: The current recommended treatment for Giant Cell Tumour (GCT) of the spine is en bloc excision. Denosumab is a monoclonal antibody reducing osteoclast activity that shows promising results when used as a neo - adjuvant treatment.
J Orthop Surg Res
January 2025
Department of Orthopaedic and Trauma Surgery, Medical Faculty, University Hospital Düsseldorf, Heinrich-Heine-University, Düsseldorf, Germany.
Background: Osteoporosis, a skeletal disorder affecting nearly 20% of the global population, poses a significant health concern, with osteoporotic vertebral body fractures (VBF) representing a common clinical manifestation. The impact of osteoporotic sintering fractures in the thoracolumbar spine on the sagittal lumbar profile is incompletely understood and may lead to the onset of clinical symptoms in previously asymptomatic patients.
Methods: This retrospective single-center study analyzed data from patients presenting with osteoporotic spine fractures between 2017 and 2022.
J Am Acad Orthop Surg Glob Res Rev
January 2025
From the Warren Alpert Medical School, Brown University, Providence, RI (Singh and Daher), and the Department of Orthopedics, Brown University, Providence, RI (Dr. Diebo, Dr. Daniels, and Dr. Arcand).
Background: Whether testosterone replacement therapy (TRT) can mitigate the risk of vertebral fractures has not been well-studied.
Methods: PearlDiver was queried to identify patients with and without the history of TRT. Groups were matched 1:1 by demographic variables and 2-year vertebral fracture incidence rate was compared.
J Bone Miner Metab
January 2025
Department of Orthopaedic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita-15 Nishi-7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.
Introduction: Proximal femoral fractures are critically associated with increased risk of mortality and secondary fractures. Identifying prognosis predictors related to sagittal imbalance that are known to have negative impact on fracture risk and mortality is crucial. This study aimed to explore the relationship between various sagittal imbalance parameters and the prognosis of proximal femoral fractures to identify the most important prognostic indicators.
View Article and Find Full Text PDFInfect Drug Resist
January 2025
Department of Orthopedics, First Affiliated Hospital, Chongqing Medical University, Chongqing, People's Republic of China.
Background: Early differentiation between spinal tuberculosis (STB) and acute osteoporotic vertebral compression fracture (OVCF) is crucial for determining the appropriate clinical management and treatment pathway, thereby significantly impacting patient outcomes.
Objective: To evaluate the efficacy of deep learning (DL) models using reconstructed sagittal CT images in the differentiation of early STB from acute OVCF, with the aim of enhancing diagnostic precision, reducing reliance on MRI and biopsies, and minimizing the risks of misdiagnosis.
Methods: Data were collected from 373 patients, with 302 patients recruited from a university-affiliated hospital serving as the training and internal validation sets, and an additional 71 patients from another university-affiliated hospital serving as the external validation set.
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