The following endocrine disturbances observed in the early postoperative period are prognostically unfavourable: persisted high blood hydrocortisone level, decreased thyroid hormone, especially T-3, values, damaged negative feedback between T-3 and TTH, decreased leucine-enkephalin blood immunoreactivity. The loss of correlation between hydrocortisone and ACTH, T-3 and TTH, insulin and glucose blood levels, as well as close correlation between hydrocortisone and insulin, hydrocortisone and glucose levels and an abrupt increase in hydrocortisone/insulin, hydrocortisone/STH, hydrocortisone/T-3 and hydrocortisone/T-4 ratios have the same predictive value.

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