Introduction: Temporal bone paragangliomas (TBPs) are benign tumors arising from neural crest cells located along the jugular bulbus and the tympanic plexus. In general surgical excision, radiotherapy and wait-and-scan protocols are the main management modalities for TBPs.
Objective: In this paper we aim to present our clinical experience with TBPs and to review literature data.
Methods: The patients who were operated for tympanomastoid paraganglioma (TMP) or tympanojugular paraganglioma (TJP) in our clinic in the last 15 years were enrolled in the study. A detailed patient's charts review was performed retrospectively.
Results: There were 18 (52.9%) cases with TMPs and 16 (47.1%) cases with TJPs, a total of 34 patients operated for TBPs in this time period. The mean age was 50.3± 11.7 (range 25-71 years). The most common presenting symptoms were tinnitus and hearing loss for both TMPs and TJPs. Gross total tumor resection was achieved in 17 (94.4%) and 10 (62.5%) cases for TMPs and TJPs, respectively. Five patients (31.2%) with TJP experienced facial palsy following the operation. For all the patients the mean follow-up period was 25.8 months (range 4-108 months).
Conclusion: In conclusion, based on our findings and literature review, total surgical excision alone or with preoperative embolization is the main treatment modality for TBPs. However radiotherapy, observation protocol and subtotal resection must be considered in cases of preoperative functioning cranial nerves, large tumors and advanced age.
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http://dx.doi.org/10.1016/j.bjorl.2016.11.001 | DOI Listing |
Mol Biol Rep
January 2025
Institute of Health Sciences, Department of Medical and Surgical Research, Hacettepe University, Ankara, Turkey.
Background: La-related protein 7 (LARP7) is a key regulator of RNA metabolism and is thought to play a role in various cellular processes. LARP7 gene autosomal recessive mutations are the cause of Alazami syndrome, which presents with skeletal abnormalities, intellectual disabilities, and facial dysmorphisms. This study aimed to determine the role of LARP7 in modulating gene expression dynamics during osteogenesis.
View Article and Find Full Text PDFJ Oral Facial Pain Headache
June 2024
Department of Maxillofacial Surgery, Lithuanian University of Health Sciences, LT-50161 Kaunas, Lithuania.
Osteoma is a rare benign tumor primarily affecting the craniofacial skeleton. Coronary osteomas in the coronoid process are uncommon and asymptomatic until they affect mandibular function. This report presents a case of coronoid osteoma with its diagnosis, treatment and surgical approach.
View Article and Find Full Text PDFRev Mal Respir
January 2025
Centre de lutte antituberculeuse de Nice, Hôpital Pasteur, 30, Voie Romaine, 06000 Nice, France. Electronic address:
Introduction: Tuberculous otomastoiditis is a rare and serious infection that most often occurs in association with pulmonary involvement. It is easy to diagnose when the two pathologies are associated and isolated. We herein report the case of a patient initially hospitalized for Pseudomonas aeruginosa necrotising otitis externa (NOE), which delayed the diagnosis of tuberculous otomastoiditis.
View Article and Find Full Text PDFOtol Neurotol
February 2025
Department of Radiology, Columbia University Irving Medical Center, New York, NY, USA.
Objective: To compare the diagnostic capability of Pöschl reformations created from temporal bone CT (TBCT) and high-resolution noncontrast CT head exams (HR-NECTH) to detect and classify superior semicircular canal (SSC) abnormalities.
Study Design: Retrospective case review.
Setting: Tertiary referral center.
Objective: The aim of this study is to test the feasibility of a custom 3D-printed guide for performing a minimally invasive cochleostomy for cochlear implantation.
Study Design: Prospective performance study.
Setting: Secondary care.
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