Anaphylaxis in the community: a questionnaire survey of members of the UK Anaphylaxis Campaign.

Objectives: To examine the circumstances, features and management of anaphylaxis in children and adults.

Design: Self-completed questionnaire.

Participants: The age of participants ranged from 0 to 72 years.

Setting: We analysed data from self-completed questionnaires collected over a 12-year period, i.e. 2001-2013, available to people by phone and, since 2012, for online completion through the Anaphylaxis Campaign.

Main Outcome Measure: We analysed data from self-completed questionnaires collected over a 12- year period, i.e. 2001-2013, available to people by phone and, since 2012, for online completion through the Anaphylaxis Campaign.

Results: In total, 356 questionnaires were submitted, of which 54 did not meet the criteria for anaphylaxis. The remaining 302 anaphylactic reactions originated from 243 individuals; 193 (64%) of these reactions were in children. Approximately half of all reactions occurred at home ( = 148; 49%); 61% ( = 193) of reactions occurred in those reporting a history of asthma, and many ( = 76; 41%) of these individuals had asthma that they classified as being severe. In 57% ( = 173) cases, the respondent reacted to a known allergen. Self-injectable adrenaline (epinephrine) was available in 79% of the cases, and it was only used in 38% of episodes. The usage of self-injected adrenaline was lower in children (30%) than in adults (54%), even though 82% of children had adrenaline available at the time of the reaction compared to 74% of adults.

Conclusions: These data suggest that the majority of anaphylaxis reactions are triggered by exposure to known food allergens and that approximately half of these reactions occur at home. Access to self-injectable adrenaline was sub-optimal and when available it was only used in a minority of cases. Avoiding triggers, access to self-injectable adrenaline and its prompt use in the context of reactions need to be reinforced.