AI Article Synopsis
- The study focused on the development of nucleolus-like bodies in neurosecretory hypothalamic neurons during differentiation.
- The research compared the nucleus supraopticus in offspring from intact rats and those whose mothers were given anti-hypothalamic antibodies, which affected hypothalamic tissue differentiation.
- The findings suggest that the presence of nucleolus-like bodies is a normal physiological occurrence associated with the functional development of neurosecretory cells, with notable morphological differences between traditional nucleoli and these bodies.
Article Abstract
The emergence of nucleolus-like bodies was studied during differentiation of neurosecretory hypothalamic neurons. Nucleus supraopticus was studied in offspring of intact rats and in offspring of mothers injected with anti-hypothalamic antibodies stimulating hypothalamic tissue differentiation during gestation. The degree of structural and functional differentiation of neurosecretory cells correlated with the number of neurosecretory cells and of neurons with nucleolus-like bodies. The authors believe that these bodies' formation is a physiological event linked to development of specific function of neurosecretory cells. Morphologically, nucleoli and nucleolus-like bodies were different, with nucleolonemms absent in the latter.
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