Purpose: To compare the movement of a modular intraocular lens (IOL) with that of a standard single-piece hydrophobic acrylic IOL in a human cadaver eye perfusion model.
Setting: Department of Ophthalmology, University of Colorado, Aurora, Colorado, USA.
Design: Experimental study.
Methods: Eight phakic human donor eyes of 4 patients had standard phacoemulsification with lens removal. One of 2 IOLs was then implanted in the capsular bag: a modular IOL (Harmoni) or a standard single-piece IOL (Acrysof SN60). Each globe was connected to a programmable perfusion pump with an in-line pressure transducer. Ultrasound biomicroscopy (UBM) was used to evaluate the anterior chamber depth (ACD) in each eye, measuring from the posterior cornea to the anterior surface of the optic at an intraocular pressure (IOP) of 5 mm Hg, 10 mm Hg, 20 mm Hg, and 30 mm Hg. Five consecutive measurements were recorded for all eyes at each pressure, and the results were averaged.
Results: There was significantly less movement in eyes with the modular IOL than in eyes with the single-piece IOL. The mean position of the modular IOL varied from a minimum of 0.03 mm to a maximum of 0.07 mm, and the mean position of the single-piece IOL varied from a minimum of 0.26 mm to a maximum of 0.87 mm (P = .002).
Conclusions: The modular IOL showed less movement with changes in IOP than a standard single-piece IOL. Improved IOL stability might allow more accuracy in determining the effective lens position and hence improve the predictability of the refractive target.
Financial Disclosure: Proprietary or commercial disclosures are listed after the references.
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http://dx.doi.org/10.1016/j.jcrs.2016.09.022 | DOI Listing |
Clin Ophthalmol
February 2024
Department of Ophthalmology, Centro Hospitalar Universitário de Santo António, Porto, Portugal.
Purpose: To perform a multimodal assessment of refractive outcomes and quality of vision (QoV) in patients with high myopia submitted to multifocal intraocular lens (IOL) implantation.
Methods: Retrospective study that included consecutive eyes with high myopia (axial length [AL] >26.00mm) submitted to multifocal IOL implantation between January 2014 and February 2020.
J Cataract Refract Surg
October 2022
From the University of California Irvine, Irvine, California (Garg); LensGen, Inc., Irvine, California (De Jesus, Fletcher, Casey); CODET Vision Institute, Tijuana, Mexico (Chayet); Dr. Enrique Barragan Private Practice, Monterrey, Mexico (Barragán).
Purpose: To report the initial safety and effectiveness profile for an anterior shape-changing, modular IOL, Juvene IOL (JIOL), for the treatment of aphakia and presbyopia after removal of the natural crystalline lens due to cataract.
Setting: 2 private practices in Monterrey and Tijuana, Mexico.
Design: Exploratory prospective multicenter open-label noncomparative clinical trial.
J Cataract Refract Surg
November 2021
From the Asian Eye Institute, Rockwell Center, Makati City, Philippines (Ang); Clarvista Medical, Inc., Aliso Viejo, California (Yoo); Alcon Vision LLC, Fort Worth, Texas (Liu).
Purpose: To evaluate the effectiveness of the Harmoni Modular IOL (HMIOL).
Setting: 3 study sites.
Design: Prospective, multicenter clinical study.
Unlabelled: The rising number of cases requiring intraocular lens (IOL) exchange, including those for refractive reasons, drives the search for methods to minimize the trauma of the procedure. Lens implants with modular optics may lower complication risks.
Purpose: To test the use of modular IOL on a laboratory animal in an experiment.
Int J Ophthalmol
January 2021
Cataract and Refractive Services, Cornea Institute, L V Prasad Eye Institute (LVPEI), Hyderabad 500034, India.
Aim: To compare the difference of capsulotomy produced by precision pulse capsulotomy (PPC), manual (M-CCC), and femtosecond laser assisted capsulotomy (FLAC) in relation to intraocular lens (IOL) centration, circularity and its effect on visual outcomes.
Methods: Prospective, non-randomized comparative study conducted at LV Prasad Eye Institute, Hyderabad, India. Sixty eyes of 52 patients were grouped into 3 (FLAC, PPC and M-CCC) based on capsulotomy techniques used.
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