AI Article Synopsis
- The study assessed how patient positioning (supine vs. prone) affects radiation dose distribution in pancreatic cancer treatment.
- A retrospective analysis of 33 patients showed that optimizing positioning can significantly reduce radiation exposure to sensitive organs like the duodenum and stomach while improving the dose to the tumor.
- Results indicated that selecting the appropriate position for each beam angle could lower organ doses and enhance tumor coverage, suggesting a potential strategy for better treatment outcomes.
Article Abstract
Purpose: Pancreatic tumor treatment dose distribution variations associated with supine and prone patient positioning were evaluated.
Methods: A total of 33 patients with pancreatic tumors who underwent CT in the supine and prone positions were analyzed retrospectively. Gross tumor volume (GTV), planning target volume (PTV), and organs at risk (OARs) (duodenum and stomach) were contoured. The prescribed dose of 55.2Gy (RBE) was planned from four beam angles (0°, 90°, 180°, and 270°). Patient collimator and compensating boli were designed for each field. Dose distributions were calculated for each field in the supine and prone positions. To improve dose distribution, patient positioning was selected from supine or prone for each beam field.
Results: Compared with conventional beam angle and patient positioning, D2cc of 1st-2nd portion of duodenum (D1-D2), 3rd-4th portion of duodenum (D3-D4), and stomach could be reduced to a maximum of 6.4Gy (RBE), 3.5Gy (RBE), and 4.5Gy (RBE) by selection of patient positioning. V10 of D1-D2, D3-D4, and stomach could be reduced to a maximum of 7.2cc, 11.3cc, and 11.5cc, respectively. D95 of GTV and PTV were improved to a maximum of 6.9% and 3.7% of the prescribed dose, respectively.
Conclusions: Optimization of patient positioning for each beam angle in treatment planning has the potential to reduce OARs dose maintaining tumor dose in pancreatic treatment.
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| http://dx.doi.org/10.1016/j.ejmp.2016.12.001 | DOI Listing |
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