Treatment for Spontaneous Intracranial Dissecting Aneurysms in Childhood: A Retrospective Study of 26 Cases.

Front Neurol

Department of Interventional Neuroradiology, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing , China.

Published: December 2016

AI Article Synopsis

  • The study focused on understanding the clinical features and outcomes of intracranial dissecting aneurysms (IDAs) in children over a five-year period.
  • A total of 26 pediatric patients were evaluated, with a significant majority undergoing endovascular or surgical treatment, resulting in a high rate of favorable outcomes.
  • Despite the effectiveness of treatment, ongoing monitoring is necessary due to risks of aneurysm recurrence or new aneurysm formation.

Article Abstract

Objective: This study aimed to assess the clinicoradiological features and treatment outcomes of intracranial dissecting aneurysms (IDAs) in childhood.

Methods: We conducted a retrospective study of pediatric patients who were treated for spontaneous IDAs in our institute between January 2010 and December 2015. The clinical presentation, aneurysm characteristics, treatment modality, and outcome were studied.

Results: We studied 26 pediatric patients (mean age, 13.4 years; range, 4-18 years) with 31 IDAs who comprised 6.9% of all IDA patients treated during the same period. Seventeen (65.4%) patients were males, and nine (34.6%) were females. The incidence of large (≥10 mm in size) or giant aneurysms (≥25 mm in size) was 65.5%. Twenty-one (80.8%) patients underwent endovascular or surgical treatment and five (19.2%) received conservative treatment. Perioperative complications occurred in three patients, in whom two eventually recovered completely with a Glasgow Outcome Scale (GOS) score of 5 and one partially recovered with a GOS score 4. Overall, 25 (96.2%) patients had a favorable outcome and one (3.8%) had an unfavorable outcome at a mean follow-up of 22.8 months (range, 6-60 months).

Conclusion: Pediatric IDAs are rare. In this series, endovascular management was a relatively safe and effective method of treatment for pediatric IDAs. However, continued follow-up is required because of the possibility of aneurysm recurrence and aneurysm formation after treatment.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138241PMC
http://dx.doi.org/10.3389/fneur.2016.00224DOI Listing

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