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Methylome evolution in plants. | LitMetric

Methylome evolution in plants.

Genome Biol

Population Epigenetics and Epigenomics, Technical University of Munich, Liesel-Beckman-Str. 2, 85354, Freising, Germany.

Published: December 2016

Despite major progress in dissecting the molecular pathways that control DNA methylation patterns in plants, little is known about the mechanisms that shape plant methylomes over evolutionary time. Drawing on recent intra- and interspecific epigenomic studies, we show that methylome evolution over long timescales is largely a byproduct of genomic changes. By contrast, methylome evolution over short timescales appears to be driven mainly by spontaneous epimutational events. We argue that novel methods based on analyses of the methylation site frequency spectrum (mSFS) of natural populations can provide deeper insights into the evolutionary forces that act at each timescale.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175322PMC
http://dx.doi.org/10.1186/s13059-016-1127-5DOI Listing

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