AI Article Synopsis
- The study assessed how signal to noise ratio (SNR) and number of gradient directions (NGD) affect the consistency of liver diffusion tensor imaging (DTI) results during multiple scans.
- Five healthy volunteers underwent a DTI scan, evaluating variations across different signal averages (NSA) and gradient directions (NGD).
- Findings showed that higher SNR enhances repeatability of DTI metrics, with minimal impact from NGD; variability among subjects was low, while intrasession repeatability was significantly better than intersession repeatability.
Article Abstract
Objective: The aim of this study was to evaluate the effect of signal to noise ratio (SNR) and number of gradient directions (NGD) on intra- and intersession repeatability of liver diffusion tensor imaging (DTI) metrics.
Methods: At each of 3 liver DTI scan sessions, liver diffusion was assessed in 5 healthy volunteers using a 6-direction DTI scan performed 9 separate times (ie, number of signal averages [NSA]). In addition, 4 combinations of NSA and NGD were acquired (NSA/NGD = 1/30, 3/10, 3/12, and 5/6) to determine the combined effect to DTI metrics, which was based on intersubject variability and intrasession (Vintra) and intersession (Vinter) repeatability.
Results: Intersubject variability was less than 20%, whereas Vintra and Vinter repeatability were less than 5% and less than 10%, respectfully. Vinter was not affected by the NGD used. Decreases in Vinter(FA), Vinter(λ1), Vinter(RD), and Vinter(MD) were observed with increasing NSA, and hence SNR.
Conclusion: Increased SNR may improve intrasession and intersession repeatability of liver DTI metrics. Scan repeatability was not influenced by NGD.
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| http://dx.doi.org/10.1097/RCT.0000000000000572 | DOI Listing |
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