Cat-Scratch Disease: A Pitfall for Lymphoma Evaluation by FDG-PET/CT.

Clin Nucl Med

From the *Nuclear Medicine Department, †Hematology Department, and ‡Histopathology Department, Hospices Civils de Lyon, Université de Lyon 1, France.

Published: February 2017

AI Article Synopsis

  • FDG-PET/CT is crucial for staging and assessing treatment response in Hodgkin lymphoma, but it can have interpretation pitfalls that affect treatment decisions.
  • A case study discusses a 29-year-old woman with stage III bulky Hodgkin lymphoma who initially showed a complete metabolic response on PET/CT.
  • After further chemotherapy, symptoms emerged, leading to the discovery of cat-scratch disease instead of lymphoma recurrence, highlighting the need for careful evaluation of imaging results.

Article Abstract

FDG-PET/CT is a standard of care in staging and response assessment of Hodgkin lymphoma. Hence, it is important to recognize pitfalls owing to the potential therapeutic impact. We report a case of a 29-year-old woman affected by stage III bulky Hodgkin lymphoma. The interim FDG-PET/CT showed a complete metabolic response. After three new cycles of chemotherapy, the patient showed fever and lymphadenopathy at clinic examination, PET/CT revealed several FDG uptakes at lymph nodes in inguinal and iliac region. Pathologic analyses, after biopsy and serologic examinations, led to the diagnosis of cat-scratch disease.

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http://dx.doi.org/10.1097/RLU.0000000000001492DOI Listing

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