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Clinico-immunological evaluation of use of omega-3 fatty acids as nutraceutical approach in management of patients with chronic periodontitis: A randomized clinical trial.
Med J Armed Forces India
May 2024
Professor (Pathology), Army Hospital (Research & Referral), New Delhi, India.
Background: Subgingival bacterial colonization and biofilm formation are known to be the main etiology of periodontal disease progression. This biofilm elicits host response and the interaction between host defence mechanisms with plaque microorganisms and their products results in periodontal disease. Host modulatory therapy (HMT) is a form of treatment of periodontitis that focuses on treatment of the host in the host-bacteria interaction.
View Article and Find Full Text PDFEvaluation of dietary supplementation of omega-3 polyunsaturated fatty acids as an adjunct to scaling and root planing on salivary interleukin-1β levels in patients with chronic periodontitis: A clinico-immunological study.
J Indian Soc Periodontol
January 2017
Department of Microbiology, JSS Medical College and Hospital, Jagadguru Sri Shivarathreeshwara University, Mysore, Karnataka, India.
Context: Host modulation with omega-3 polyunsaturated fatty acids (ω-3 PUFAs) has anti-inflammatory and pro-resolution actions through replacing and inhibiting metabolism of arachidonic acid (AA).
Aim: This study was aimed at evaluating clinical parameters and salivary levels of interleukin-1 beta (IL-1β) after scaling and root planing (SRP) in chronic periodontitis patients, with and without dietary supplementation of ω-3 PUFAs.
Settings And Design: Forty otherwise healthy participants with severe chronic periodontitis were included.
[Immunological aspects of delayed regeneration of mandibular fractures].
Georgian Med News
April 2015
SE «Dnipropetrovsk medical academy Ministry of Health of Ukraine», Dnipropetrovsk, Ukraine.
The level of complications in patients with the mandibular fractures does not have a tendency to the decline. A research purposes is a study of the basic laws of immunological reactions and possibility of optimizing processes osteogenesis by drugs-cytokines at patients with the mandibular fractures with delayed consolidation of bone tissue. 46 patients with the mandibular fractures were observed.
View Article and Find Full Text PDFAssessment of clinico-immunological profile of newly diagnosed HIV patients presenting to a teaching hospital of eastern India.
Indian J Med Res
June 2014
Department of Medicine, Medical Collge, Kolkata, India.
Background & Objectives: Newly diagnosed HIV patients may be asymptomatic or present with a wide range of symptoms related to opportunistic infections, acute seroconversion illness or other medical illnesses. This study was designed to evaluate the socio-demographic parameters, spectrum of the presenting clinical conditions and concurrent immunological status of newly diagnosed HIV patients and document the WHO clinical stages at the time of HIV diagnosis.
Methods: This cross-sectional, observational study was undertaken over a 12 month period at a tertiary referral hospital in eastern India.
Clinico-immunological response to intratumoral versus intravenous neoadjuvant chemotherapy in advanced pediatric solid malignancies.
Indian J Med Paediatr Oncol
April 2013
Department of Pediatric Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Background: There is minimal literature on the use of intralesional chemotherapy in the pediatric age group. We undertook this present study to evaluate the two modalities (intratumoral and intravenous) of giving chemotherapy in terms of toxicity of chemotherapy, hematological parameters, efficacy of chemotherapy in reduction in volume of the tumor as well as resectability of tumor with special emphasis on immunological parameters.
Materials And Methods: Advanced cases of Wilms' tumor and Neuroblastoma were included in the study.
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