Activity of cystylaminopeptidase (CAP) was established repeatedly in the blood serum of 40 healthy women since the 14th to the 37th week of pregnancy by means of method using S-benzyl-L-cystein-p-nitranilid as substrate. Continuous increase of values was observed, more moderate up to the 28th week, later sheerer, with a certain dispersion in examination of different women in the same length of pregnancy. No statistically significant dependency was found out by evaluating different influences on the CAP activity (weight, length, and sex of the infant, time of gestation and age of mother at delivery). Interindividual differences in the CAP activity are significantly higher than differences individually evaluated in the course of pregnancy.
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