Partial hypopituitarism in a female patient with a 45,X/46,XY mosaicism.

Ann Endocrinol (Paris)

Unité d'endocrinologie, service de médecine interne A, hôpital Charles-Nicolle, faculté de médecine de Tunis, université de Tunis El Manar, boulevard du 9-Avril, Bab souika, 1006 Tunis, Tunisia.

Published: February 2017

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ando.2016.09.003DOI Listing

Publication Analysis

Top Keywords

partial hypopituitarism
4
hypopituitarism female
4
female patient
4
patient 45x/46xy
4
45x/46xy mosaicism
4
partial
1
female
1
patient
1
45x/46xy
1
mosaicism
1

Similar Publications

Neurosarcoidosis (NS) is a rare form of sarcoidosis, with isolated hypothalamic-pituitary involvement being exceptionally uncommon. We report a 20-year-old woman presenting with polyuria, galactorrhea, amenorrhea, and substantial weight loss. Hormonal evaluation revealed hypopituitarism with arginine-vasopressin deficiency and hyperprolactinemia.

View Article and Find Full Text PDF

Cyberknife radio-neurosurgery for secreting pituitary adenomas treated with single fraction radio-neurosurgery: A systematic review and meta-analysis.

J Clin Neurosci

January 2025

Lausanne University Hospital (CHUV), Neurosurgery Service and Gamma Knife Center, Switzerland; University of Lausanne (UNIL), Faculty of Biology and Medicine (FBM), Switzerland; Ecole Polytechnique Fédérale de Lausanne (EPFL, LTS-5), Switzerland. Electronic address:

Introduction: Stereotactic radiosurgery (SRS) is one of the treatment options for the management of residual or recurrent secreting pituitary adenomas (PA). While the role of radiosurgery (RS) by Gamma Knife (GK) has been clearly established, Cyberknife (CK) RS has been evaluated in fewer series.

Material And Methods: To perform a systematic review of the literature and meta-analysis, with the aim of focusing on the effect of CK RS on secreting PA.

View Article and Find Full Text PDF
Article Synopsis
  • Pituitary adenomas often lead to the need for Gamma Knife radiosurgery (GKRS) after incomplete removal or recurrence, and this study aims to assess its long-term effectiveness.
  • In a cohort study of 147 patients who underwent GKRS between 1999 and 2020, the researchers evaluated progression-free survival (PFS) over an average follow-up of 8.1 years, finding a 5-year PFS of 86% and a 10-year PFS of 68%.
  • Results indicated that somatotrophic adenomas had lower progression risks, but 32% of patients experienced adverse radiation events, mainly hypopituitarism, highlighting the need to weigh outcomes against potential side effects.
View Article and Find Full Text PDF

Background: Thyroid function tests (TFTs) are routinely requested by general practitioners (GPs) in the clinical biochemistry laboratory. Hypothyroxinaemia (low fT4) accompanied by TSH within the reference interval (RI) is a discordant pattern which is seen commonly in non-thyroidal illness and also as result of medications. Hypopituitarism is a lot rarer, but a serious condition the laboratory does not want to miss.

View Article and Find Full Text PDF
Article Synopsis
  • - Hypopituitarism is a rare condition characterized by the absence of pituitary hormones, often caused by tumors or other masses, and diagnosed using MRI; intrasellar aneurysms are an uncommon cause, accounting for about 0.17% of cases.
  • - A case study of a 72-year-old man highlights the connection between gastrointestinal issues and hypopituitarism, where he was found to have an unruptured internal carotid artery aneurysm, leading to panhypopituitarism.
  • - After a stent-assisted coil embolization to treat the aneurysm and hormonal therapy, the patient showed no improvement in pituitary function after one year, emphasizing that hypopituitarism can persist
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!