The world-wide use of concentrated animal feeding operations (CAFOs) for livestock production demands the need to evaluate the potential impact to public health. We estimated the exposure of various airborne pollutants for populations residing in close proximity to 10 poultry CAFOs located in Central Poland. Ammonia (NH), carbon dioxide (CO), carbon monoxide (CO), hydrogen sulfide (HS), methane (CH), nitrogen dioxide (NO), nitrous oxide (NO), sulfur dioxide (SO), and organic dust were the pollutants of interest for this study. Because no monitoring data were available, we used the steady-state Gaussian dispersion model AERMOD to estimate pollutant concentrations for the exposed population in order to calculate the hazard index (HI) for a combined mixture of chemicals. Our results indicate that while the levels of certain pollutants are expected to exceed background levels commonly found in the environment they did not result in calculated hazard indexes which exceeded unity suggesting low potential for adverse health effects for the surrounding community for the mixture of chemicals. The study was conducted through a cooperation between the Agency for Toxic Substances and Disease Registry (ATSDR) in the USA and the Nofer Institute of Occupational Medicine (NIOM) in Poland.
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http://dx.doi.org/10.1016/j.yrtph.2016.11.005 | DOI Listing |
J Clin Endocrinol Metab
January 2025
Department of Neurosurgery and State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital; Chongqing Key Laboratory of Precision Neuromedicine and Neuroregenaration, Third Military Medical University (Army Medical University), 400038 Chongqing, China.
Background: Phthalates, widely used as chemical additives, are often found as mixtures in the environment. However, the combined impact of phthalate exposure on sarcopenia remains unclear.
Objective: This study aimed to investigate the relationships between phthalates and sarcopenia in adults.
Environ Sci Technol
January 2025
Nicholas School of the Environment, Duke University, Durham, North Carolina 27708, United States.
Pet dogs offer valuable models for studying environmental impacts on human health due to shared environments and a shorter latency period for cancer development. We assessed environmental chemical exposures in a case-control study involving dogs at high risk of urothelial carcinoma, identified by a BRAF V595E mutation in urinary epithelial cells. Cases ( = 25) exhibited low-level BRAF mutations, while controls ( = 76) were matched dogs without the mutation.
View Article and Find Full Text PDFJ Phys Chem Lett
January 2025
International Tomography Center, SB RAS, 3A Institutskaya St., Novosibirsk 630090, Russia.
Nuclear magnetic resonance is extremely attractive for operando studies of chemical reactors. However, the heterogeneous catalyst particles placed inside an NMR probe greatly affect the uniformity of the magnetic field. This problem is especially acute when studying heterogeneous hydrogenation processes using parahydrogen.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Univ Rennes, Inserm, EHESP, Irset (Institut de Recherche en Santé, Environnement et Travail), Rennes, NA, France.
Chemicals are ubiquitous in modern life. More than 100,000 chemicals are currently used worldwide, and the production continues to increase. Measuring with accuracy all the components of the chemical exposome represents a tremendous challenge which has been only very partly met so far, and gaps in science remain multiple.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Mailman School of Public Health, Columbia University, New York, NY, USA.
Exposure to environmental chemicals has been associated with Alzheimer's disease (AD); however, most studies have used a targeted approach to study this relationship. While targeted approaches have been critical to understand mechanisms, they do not reflect real world exposures where an individual is exposed to multiple chemicals at the same time. Exposomics provides the opportunity to use an -omics level approach to understand the environmental drivers of disease by measuring the burden of multiple chemicals at the same time.
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