AI Article Synopsis
- Historically, stage IV prostate cancer was viewed as incurable, but some cases may be treatable with aggressive multimodal treatments.
- Node-positive and oligometastatic prostate cancers are both categorized as stage IV, yet they likely represent different clinical groups with varying outcomes.
- While randomized evidence is limited, retrospective studies indicate that treatments like radical prostatectomy or radiotherapy could enhance survival, highlighting the need for more research and clinical trials in this area.
Article Abstract
Historically, stage IV prostate cancer was considered incurable. Although node-positive and oligometastatic prostate cancers are both classified as stage IV, these likely represent distinct clinical groups, and some patients may be curable with aggressive multimodality treatments. There is a lack of randomized evidence, but retrospective studies suggest that radical prostatectomy or radiotherapy may improve survival in these patients. This is an area of great current research interest and prospective randomized trials are needed to help define the optimal treatments for these patients.
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| http://dx.doi.org/10.1016/j.semradonc.2016.08.006 | DOI Listing |
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