An organocatalytic enantioselective aldol reaction using paraformaldehyde as C1-unit has been developed for the synthesis of 2-oxindoles sharing vicinal all-carbon quaternary stereocenters. The methodology is eventually employed in the formal total synthesis of (+)-folicanthine (1b).
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.joc.6b02195 | DOI Listing |
Publication Analysis
Top Keywords
synthesis 2-oxindoles
8
2-oxindoles sharing
8
sharing vicinal
8
vicinal all-carbon
8
all-carbon quaternary
8
quaternary stereocenters
8
aldol reaction
8
stereocenters organocatalytic
4
organocatalytic aldol
4
reaction organocatalytic
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!