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Association between physical activity and cognitive function in post-menopausal women with high parity: the chain-mediating effects of nutritional status and depression.
BMC Womens Health
January 2025
Department of Laboratory Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Background: It has been reported that the cognitive responses to physical activity (PA) in postmenopausal women vary by parity status, and women with higher parity show a significant association between PA and cognitive function. However, the potential pathways mediating the relationship between PA and cognitive function in women with higher parity remain unclear. The objective of this study was to examine this association in Chinese cohort and further investigate the mediating pathways.
View Article and Find Full Text PDFAssociation of age at menopause with type 2 diabetes mellitus in postmenopausal women: a systematic review and meta-analysis.
Prz Menopauzalny
December 2024
Department of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
The onset of menopause usually occurs between the ages of 48 and 52, leading to diverse symptoms in various body systems due to a decrease in estrogen level. Visceral obesity and diminished estrogen level during the menopausal phase are associated with unfavorable metabolic changes, resulting in insulin resistance and increased risk of type 2 diabetes mellitus (T2DM). Owing to the increase in the incidence and prevalence of T2DM in recent decades, it is important to identify predisposing factor such as menopausal age to improve T2DM prevention and management.
View Article and Find Full Text PDFLife stage impact on the human skin ecosystem: lipids and the microbial community.
NPJ Biofilms Microbiomes
January 2025
A*STAR Skin Research Labs (A*SRL), Agency for Science, Technology, and Research (A*STAR) & Skin Research Institute of Singapore (SRIS), Singapore, Republic of Singapore.
Article Synopsis
- The study examines the relationship between skin oxylipins, which are bioactive lipids produced from fatty acids by skin microbes, and different microbial communities on the skin of children and adults.
- Findings highlighted that Malassezia restricta, a type of skin fungus, has a positive impact on the production of a specific oxylipin (9,10-DiHOME) in adults, while showing a negative correlation with its precursor in children, indicating differences in skin chemistry across age groups.
- The research suggests a complex communication system between skin microbes and host lipid metabolism that could have implications for skin health, emphasizing the need for further exploration of these interactions for potential therapeutic applications.
Assessing the influence of recurrent urinary tract infections on sexual function: a case-control study.
J Sex Med
January 2025
Department of Urology, Hospital Universitario 12 de Octubre-imas12, Madrid, 28040, Spain.
Background: Urinary tract infections (UTIs) significantly impact quality of life and can also lead to changes in sexual function.
Aim: This study aims to assess the symptoms associated with recurrent urinary tract infections (rUTIs) and their influence on both quality of life and sexual activity.
Methods: A case-control study was conducted, involving 383 patients with rUTIs and 161 healthy controls.
Sex Differences, Menses-Related Symptoms and Menopause in Disorders of Gut-Brain Interaction.
Neurogastroenterol Motil
January 2025
University of California Los Angeles David Geffen School of Medicine, California, Los Angeles, USA.
Background: Disorders of gut-brain interaction (DGBI) predominate in women, but little is known about sex differences in menses-related or menopause symptoms.
Methods: Using data from the Rome Foundation Global Epidemiology Survey, we assessed Rome IV DGBI symptoms in individuals in 26 countries who met criteria for ≥ 1 of 5 DGBI: irritable bowel syndrome (IBS), functional dyspepsia (FD), functional constipation (FC), functional diarrhea (FDr), or functional bloating (FB). Participants included pre- and post-menopausal women with DGBI and age-matched men.
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