Probe L-HF1, which featured large (pseudo) Stokes shifts and high FRET efficiency, was designed on a new ESIPT enhanced FRET platform for the detection of HSO/SO. L-HF1 could detect endogenous bisulfite in HepG2 cells but not in L-02 cells, implying the different bisulfite levels in normal and cancer cells of liver.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c6cc06459k | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
TET3-facilitated differentiation of human umbilical cord mesenchymal stem cells into oligodendrocyte precursor cells for spinal cord injury recovery.
J Transl Med
December 2024
Department of Orthopaedic Surgery, The First Affiliated Hospital of Harbin Medical University, 2075 Qunli Seventh Avenue, Daoli District, Harbin, 150001, Heilongjiang Province, China.
Background: Spinal cord injury (SCI) inflicts a severe burden on patients and lacks effective treatments. Owing to the poor regenerative capabilities of endogenous oligodendrocyte precursor cells (OPCs) following SCI, there is a growing interest in alternative sources, such as human umbilical cord mesenchymal stem cells (HUCMSCs). TET3 is a key DNA demethylase that plays an important role in neural differentiation, but its role in OPC formation is not well understood.
View Article and Find Full Text PDFNear-infrared xanthene fluorescence probe for frequency upconversion fluorescence detection of HSO in evaluation of drug-induced hepatotoxicity.
Spectrochim Acta A Mol Biomol Spectrosc
November 2024
Jiangxi Provincial Key Laboratory of Synthetic Pharmaceutical Chemistry, College of Chemistry and Chemical Engineering, Gannan Normal University, Ganzhou 341000, PR China. Electronic address:
Article Synopsis
- * A newly designed FUCL probe, PT-1, shows high sensitivity and selectivity in detecting HSO, with a detection limit significantly lower than traditional methods (43 nM vs. 93 nM).
- * PT-1 not only targets mitochondria for real-time monitoring of HSO in living cells but also successfully tracks HSO levels in mice experiencing drug-induced liver injury using FUCL imaging.
Rational design of an ultrabright quinolinium-fused rhodamine turn-on fluorescent probe for highly sensitive detection of SO derivatives: Applications in food safety and bioimaging.
J Hazard Mater
December 2024
College of Chemistry and Materials Engineering, Bohai University, Jinzhou 121013, PR China. Electronic address:
Sulfur dioxide (SO) is an essential signaling molecule involved in various physiological processes within living organisms. Bisulfite (HSO) possesses antioxidant, antimicrobial, and preservative properties, making it a common food additive. However, elevated levels of SO or excessive HSO intake can lead to a range of diseases, highlighting the importance of detecting SO and its derivatives (HSO/SO).
View Article and Find Full Text PDFEndogenous viral elements are targeted by RNA silencing pathways in banana.
New Phytol
November 2024
CIRAD, UMR AGAP Institut, Montpellier, F-34398, France.
Article Synopsis
- Endogenous banana streak virus (eBSV) integrants from Musa balbisiana can reactivate in AAB hybrids, leading to banana streak disease, but not in BB parent lines with similar eBSV loci.
- Research utilized sequencing to analyze siRNAs, transcripts, and methylation levels in both eBSV-free and eBSV-infected banana plants.
- The results indicate that eBSV regulation is epigenetic in BB plants, preventing viral activation and contributing to their resistance against viral infections.
A FRET/TICT based multifunctional fluorescent probe for the monitoring of SO derivatives and viscosity in living cells and real samples.
Spectrochim Acta A Mol Biomol Spectrosc
January 2025
School of Public Health, Jining Medical University, Jining, Shandong 272067, PR China. Electronic address:
SO derivatives and viscosity are important intracellular indicators, which are closely associated with various physiological metabolisms in organisms. The unregulated contents of SO derivatives and viscosity in vivo commonly related to some disorders. In this work, probe JFT was developed relying on FRET and TICT mechanisms for the simultaneous detection of SO derivatives and viscosity.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!