Two hundred Dutch paediatricians were invited to give their description and interpretation of the concept of 'circumoral cyanosis'. Analysis of the results shows great inter-doctor variability: 63% considered the circumoral cyanosis as a pathologic sign and 70% as an expression of central cyanosis, although in textbooks and publications this sign is defined as an expression of peripheral cyanosis and is not considered to be pathological.
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DL is an 8-year-old Mexican boy with a posterior atrial septal defect and partial anomalous pulmonary venous return of the right lower pulmonary vein with resultant right heart dilation with normal right ventricular systolic and diastolic function and no arrhythmias. Surgical repair was deferred, and DL's condition was being medically managed with furosemide 0.5 mg/kg BID and spironolactone 0.
View Article and Find Full Text PDFZhongguo Dang Dai Er Ke Za Zhi
March 2021
Guiyang Maternity and Child Health Care Hospital, Guiyang 550003, China.
This is a case report on a 1-day-old male neonate admitted due to a weak cry for 1 day and recurrent circumoral cyanosis for 2 hours. He had unusual facial features at birth, with a single transverse palmar crease on both hands, flat feet, weak cry, feeding difficulties, congenital heart disease, and abnormality on cerebral MRI. Whole exome sequencing showed a mutation, c.
View Article and Find Full Text PDFBMC Pediatr
August 2020
Pediatric Residency Program, Indiana University School of Medicine, Indianapolis, IN, USA.
Background: Data regarding coronavirus disease 2019 (COVID-19) cases and outcomes in infants are sparse compared to older pediatric and adult populations.
Case Presentation: We present a three-week-old full-term male with a history of mild hypoxic ischemic encephalopathy (HIE) who was admitted as an inpatient twice for episodes of apnea and perioral cyanosis. The patient tested positive for COVID-19 and negative for other common respiratory viruses at both admissions.
Pediatr Dermatol
January 2015
Department of Dermatology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Hutchinson-Gilford progeria syndrome (HGPS) is a rare, uniformly fatal, premature aging disease with distinct dermatologic features. We sought to identify and describe the initial skin and hair findings as potential diagnostic signs of the disease. We performed a chart review of the structured initial intake histories of 39 individuals with HGPS enrolled in clinical trials from 2007 to 2010 at Boston Children's Hospital, limited to cutaneous history from birth to 24 months.
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