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A simply triggered peptide-based hydrogel as an injectable nanocarrier of tanshinone IIA and tanshinones. | LitMetric
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A simply triggered peptide-based hydrogel as an injectable nanocarrier of tanshinone IIA and tanshinones.

Yajun Yin Can Wu Junling Wang Fengjuan Song Wanqing Yue Wenying Zhong

Chem Commun (Camb)

Department of Analytical Chemistry, China Pharmaceutical University, Nanjing, China and Key Laboratory of Biomedical Functional Materials, China Pharmaceutical University, Nanjing 210009, P. R. China.

Published: January 2017

An easily self-assembled and gelated octa-peptide FHFDFHFD was chosen as a novel drug delivery system (DDS) for both tanshinone IIA and total tanshinone extract. The DDS showed increased loading capacity, sustained drug release and better anticancer capability. Our research proved that a hydrogel DDS of other traditional Chinese medicines is possible.

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 Source
http://dx.doi.org/10.1039/c6cc08502dDOI Listing

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