AI Article Synopsis
- * The outbreak occurred from October 26-29, 2015, affecting 28 individuals (22 residents and 6 staff), with an overall attack rate of 25.9% and higher rates in residents (8.5%).
- * Genetic analysis revealed that a single rotavirus strain was responsible for the outbreak, highlighting the need to consider RVA in investigations and prompting discussions on the potential benefits of RVA vaccines for the elderly.
Article Abstract
The present study described a group A rotavirus (RVA) outbreak in an age-care facility in Brazil, using epidemiologic and molecular diagnostic methods. A descriptive clinical, epidemiological and environmental investigation was conducted. Stool samples were collected and screened for RVA, Norovirus (NoV), Enteric Adenovirus 40/41 (AdV 40/41) and Astrovirus (AstV) using ELISA, RT-PCR, qRT-PCR, electron microscopy and sequencing methods. Outbreak occurred during 26th-29th October, 2015; 28 individuals affected (22 residents; 6 staff). The attack rate was 25.9% and 8.5% among residents (median-age: 85.5 years) and staff (median-age: 28 years), respectively. Female staff was identified as the index case. RVA G2P[4] genotype was detected in 87.5% (7/8). Genetic analysis demonstrated that the outbreak involved one single strain, suggesting a common-source infection. RVA should be considered during outbreaks investigations in residential facilities, and raise the question if the current licensed RVA vaccines for children could also be helpful for the elderly.
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| http://dx.doi.org/10.1016/j.gerinurse.2016.11.004 | DOI Listing |
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