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Segmented slant hole collimator for stationary cardiac SPECT: Monte Carlo simulations.

Med Phys

September 2015

Department of Radiology, Utah Center for Advanced Imaging Research (UCAIR), University of Utah, Salt Lake City, Utah 84108 and Department of Engineering, Weber State University, Ogden, Utah 84408.

Purpose: This work is a preliminary study of a stationary cardiac SPECT system. The goal of this research is to propose a stationary cardiac SPECT system using segmented slant-hole collimators and to perform computer simulations to test the feasibility. Compared to the rotational SPECT, a stationary system has a benefit of acquiring temporally consistent projections.

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Geometric Calibration and Image Reconstruction for a Segmented Slant-Hole Stationary Cardiac SPECT System.

J Nucl Med Technol

June 2015

Utah Center for Advanced Imaging Research (UCAIR), Department of Radiology, University of Utah, Salt Lake City, Utah Department of Engineering, Weber State University, Ogden, Utah.

Unlabelled: A dedicated stationary cardiac single-photon emission computed tomography (SPECT) system with a novel segmented slant-hole collimator has been developed. The goal of this paper is to calibrate this new imaging geometry with a point source.

Methods: Unlike the commercially available dedicated cardiac SPECT systems, which are specialized and can be used only to image the heart, our proposed cardiac system is based on a conventional SPECT system but with a segmented slant-hole collimator replacing the collimator.

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Myocardial perfusion SPECT using a rotating multi-segment slant-hole collimator.

Med Phys

April 2010

Department of Radiology and Radiological Sciences, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21287, USA.

Purpose: A rotating multi-segment slant-hole (RMSSH) collimator is able to provide much higher (approximately 3 times for four-segment collimator with 30 degrees slant angle) sensitivity than a parallel-hole (PH) collimator with the similar spatial resolution for imaging small organs such as the heart and the breast. In this article, the authors evaluated the performance of myocardial perfusion SPECT (MPS) using a RMSSH collimator compared to MPS using the low-energy high-resolution parallel-hole collimators.

Methods: The authors conducted computer simulation studies using the NURBS-based cardiac-torso phantom, receiver operative characteristic (ROC) analysis using the channelized Hotelling observer, physical phantom experiments, and pilot patient studies to evaluate the performance of MPS using a rotating four-segment slant-hole (R4SSH) collimator with respect to MPS using a PH collimator.

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This work applies a previously developed analytical algorithm to the reconstruction problem in a rotating multi-segment slant-hole (RMSSH) SPECT system. The RMSSH collimator has greater detection efficiency than the parallel-hole collimator with comparable spatial resolution at the expense of limited common volume-of-view (CVOV) and is therefore suitable for detecting low-contrast lesions in breast, cardiac and brain imaging. The absorption of gamma photons in both the human breast and brain can be assu- med to follow an exponential rule with a constant attenuation coefficient.

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Rotating multisegment slant-hole (RMSSH) single photon emission computed tomography (SPECT) is suitable for detecting small and low-contrast breast lesions since it has much higher detection efficiency than conventional SPECT with a parallel-hole collimator and can image the breast at a closer distance. Our RMSSH SPECT reconstruction extends a previous rotation-shear transformation-based method to include nonuniform attenuation and collimator-detector response (CDR) compensation. To evaluate our reconstruction method, we performed two phantom simulation studies with 1) an isolated breast and 2) a breast phantom attached to the body torso.

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