NIR upconversion fluorescence glucose sensing and glucose-responsive insulin release of carbon dot-immobilized hybrid microgels at physiological pH.

Nanoscale

Department of Chemistry of The College of Staten Island of the City University of New York, Staten Island, NY 10314, USA. and Ph.D. Program in Chemistry, The Graduate Center of the City University of New York, New York, NY 10016, USA.

Published: January 2017

This work reports the preparation of multifunctional hybrid microgels based on the one-pot free radical dispersion polymerization of hydrogen-bonding complexes in water, formed from hydroxyl/carboxyl bearing carbon dots with 4-vinylphenylboronic acid and acrylamide comonomers, which can realize the simultaneous optical detection of glucose using near infrared light and glucose-responsive insulin delivery.

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http://dx.doi.org/10.1039/c6nr07818dDOI Listing

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