We report the first case of infection of the human esophagus. We demonstrate initial endoscopic diagnosis, progression and then spontaneous resolution of infection, once the patient's occupational exposure had ceased.
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http://dx.doi.org/10.4021/gr216w | DOI Listing |
Mathematical modeling of somatic evolution, a process impacting both host cells and microbial communities in the human body, can capture important dynamics driving carcinogenesis. Here we considered models for esophageal adenocarcinoma (EAC), a cancer that has dramatically increased in incidence over the past few decades in Western populations, with high case fatality rates due to late-stage diagnoses. Despite advancements in genomic analyses of the precursor Barrett's esophagus (BE), prevention of late-stage EAC remains a significant clinical challenge.
View Article and Find Full Text PDFIntroduction: Acute esophageal necrosis (AEN) is a rare and lethal condition that may progress to sepsis and perforations. Most related literature comes from case reports; however, a few small reviews have been published. We conducted a large systematic review of AEN using PubMed, MEDLINE, and Embase to organize data into one consolidated manuscript, find potential prognosticators of illness, and determine possible treatment guidelines for AEN.
View Article and Find Full Text PDFZhonghua Bing Li Xue Za Zhi
February 2025
Department of Pathology, West China Hospital, Sichuan University, Chengdu 610041, China.
This case report presents a rare occurrence of Sarcina ventriculi in a 15-year-old male patient with a clinical history of renal failure due to chronic rejection status post kidney transplantation, with persistent symptoms of diarrhea, nausea, vomiting, and fatigue. Despite exhibiting normal gastrointestinal mucosa upon endoscopy, biopsy analysis revealed chronic gastritis accompanied by the presence of Sarcina ventriculi in a tetrad arrangement across the stomach, duodenum, and distal esophagus. Interestingly, immunohistochemistry (IHC) staining targeting the Helicobacter pylori organism (H.
View Article and Find Full Text PDFCureus
December 2024
Infectious Diseases Service, Pedro Hispano Hospital - Matosinhos Local Health Unit, Matosinhos, Porto, PRT.
is a facultative anaerobic Gram-negative coccobacillus that represents a rare cause of systemic infection in immunocompromised patients. This report presents the case of a 59-year-old man with advanced squamous cell carcinoma of the oesophagus, recently undergoing radiotherapy and chemotherapy, halted due to cytopenias, including neutropenia. The patient, who owned a cat but denied any recent bites or scratches, developed bacteremia caused by with presumed pulmonary and renal foci.
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