Genetic evaluation using animal model with relationship grouping has been shown to be feasible. However, algorithms were unavailable for prediction error variance and REML estimation of variance components. This paper shows that prediction error variance of an estimable function of the total merit of additive genetic and group effects is a simple function of a generalized inverse of the coefficient matrix for a transformed mixed model equation or of the inverse of the coefficient matrix when it is restricted to full rank. The REML algorithms, using the transformed equation, having slightly more complicated expressions than usual but could be more feasible computationally. Formulae for prediction error variance apply in general. The REML algorithms are extended to an animal model with an arbitrary number of random factors and can be extended to estimate covariance components.
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http://dx.doi.org/10.3168/jds.S0022-0302(89)79337-1 | DOI Listing |
ACS Sens
January 2025
Department of Physics and Astronomy, Franklin College of Arts and Sciences, The University of Georgia, Athens, Georgia 30602, United States.
Multiple respiratory viruses can concurrently or sequentially infect the respiratory tract, making their identification crucial for diagnosis, treatment, and disease management. We present a label-free diagnostic platform integrating surface-enhanced Raman scattering (SERS) with deep learning for rapid, quantitative detection of respiratory virus coinfections. Using sensitive silica-coated silver nanorod array substrates, over 1.
View Article and Find Full Text PDFRadiol Med
January 2025
Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong.
Purpose: Bodyweight loss is commonly found in Nasopharyngeal Carcinoma patients during Concurrent Chemo-radiotherapy (CCRT) and has implications for treatment decisions. However, the prognostic value of this weight loss remains uncertain. We addressed it by proposing a novel index Weight Censorial Score (WCS) that characterizes the patient-specific CCRT response on actual to estimated weight loss.
View Article and Find Full Text PDFRadiology
January 2025
From the Departments of Biomedical Systems Informatics (S.K., Jaewoong Kim, C.H., D.Y.) and Neurology (Joonho Kim, J.Y.), Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea; Department of Radiology, Central Draft Physical Examination Office of Military Manpower Administration, Daegu, Republic of Korea (D.K.); Department of Radiology, Research Institute of Radiological Science and Center for Clinical Imaging Data Science (H.J.S. Y.K., S.J.), and Center for Digital Health (H.J.S., D.Y.), Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Republic of Korea; Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea (S.H.L.); Departments of Radiology (M.H.) and Neurology (S.J.L.), Ajou University Hospital, Ajou University School of Medicine, Suwon, Republic of Korea; and Institute for Innovation in Digital Healthcare, Severance Hospital, Seoul, Republic of Korea (D.Y.).
Background The increasing workload of radiologists can lead to burnout and errors in radiology reports. Large language models, such as OpenAI's GPT-4, hold promise as error revision tools for radiology. Purpose To test the feasibility of GPT-4 use by determining its error detection, reasoning, and revision performance on head CT reports with varying error types and to validate its clinical utility by comparison with human readers.
View Article and Find Full Text PDFWorld J Gastrointest Surg
January 2025
Department of Colorectal Surgery, Sir Run Shaw Hospital Affiliated with Zhejiang University, Hangzhou 310016, Zhejiang Province, China.
Background: Despite improved survival rates in rectal cancer treatment, many patients experience low anterior resection syndrome (LARS). The preoperative LARS score (POLARS) aims to address the limitations of LARS assessment by predicting outcomes preoperatively to enhance surgical planning.
Aim: To investigate the predictive accuracy of POLARS in assessing the occurrence of LARS.
Front Radiol
January 2025
Department of Biostatistics & Informatics, Colorado School of Public Health, Aurora, CO, United States.
In neuro-oncology, MR imaging is crucial for obtaining detailed brain images to identify neoplasms, plan treatment, guide surgical intervention, and monitor the tumor's response. Recent AI advances in neuroimaging have promising applications in neuro-oncology, including guiding clinical decisions and improving patient management. However, the lack of clarity on how AI arrives at predictions has hindered its clinical translation.
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