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The Functional Interaction Between Epstein-Barr Virus and MYC in the Pathogenesis of Burkitt Lymphoma.
Cancers (Basel)
December 2024
Instituto de Biomedicina y Biotecnología de Cantabria, Departamento de Biología Molecular, Universidad de Cantabria-CSIC, Albert Einstein 22, 39011 Cantabria, Spain.
The Epstein-Barr virus (EBV) is associated with a wide range of diseases, malignant and non-malignant. EBV was, in fact, the first virus described with cell transformation capacity, discovered by Epstein in 1964 in lymphoma samples from African children. Since then, EBV has been associated with several human tumors including nasopharyngeal carcinoma, gastric carcinoma, T-cell lymphoma, Hodgkin lymphoma, diffuse large B cell lymphoma, and Burkitt lymphoma among others.
View Article and Find Full Text PDFBurkitt lymphoma after adult liver transplantation: a case report and literature review.
Front Oncol
December 2024
Department of Hepatobiliary Surgery of General Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Preface And Importance: Burkitt's lymphoma (BL) is a relatively rare post-transplant lymphoproliferative disorder (PTLD), and there is currently limited research on the occurrence of BL following adult liver transplantation.
Case Introduction: We report a 45-year-old male who developed BL that rapidly progressed at seven years after left liver transplantation. The patient eventually abandoned treatment due to severe clinical complications.
Spontaneous Tumor Lysis Syndrome in a Thoracic Burkitt Lymphoma: A Case Report.
Cureus
November 2024
Hematology, Centro Hospitalar de Setúbal, Hospital de São Bernardo, Setúbal, PRT.
Burkitt lymphoma has a high proliferation rate and a significant risk of tumor lysis syndrome. Risk stratification and early identification are imperative since it is an oncological emergency. We report the case of a 20-year-old woman, without relevant past medical history, admitted to the Emergency Department with a three-week history of fatigue, chest discomfort, productive cough, night sweats, myalgia, odynophagia, and holocranial headache.
View Article and Find Full Text PDFPrimary Gastric Atypical Burkitt Lymphoma: A Rare Case Report.
J Investig Med High Impact Case Rep
November 2024
Division of Hematology/Oncology, Brookdale University Hospital Medical Center, Brooklyn, NY, USA.
Article Synopsis
- Sporadic Burkitt lymphoma (BL) usually affects the abdomen, especially the ileocecal area, while stomach involvement is extremely rare.
- This case report highlights a unique instance of atypical Burkitt lymphoma that originated in the stomach, which has not been previously documented.
- Diagnostic tests showed positive markers like CD20 and the c-MYC gene rearrangement, but the common translocations related to Burkitt lymphoma were not present.
Burkitt's lymphoma with multi-organ involvement.
Int J Surg Case Rep
December 2024
Department of Pathology, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Article Synopsis
- Burkitt's lymphoma (BL) is a fast-growing B-cell non-Hodgkin lymphoma that often affects multiple organs, including rare cases in the gastrointestinal tract, which makes up less than 2% of small intestinal cancers.!* -
- A 34-year-old man with sickle cell trait showed symptoms like abdominal pain and weight loss, and after imaging and surgery, he was diagnosed with Burkitt's lymphoma that affected his cecum, appendix, peritoneum, and bone marrow.!* -
- The case emphasizes the significance of recognizing the fast progression of BL and the "starry sky" pattern in histopathology for accurate diagnosis and correlation in clinical settings.!*
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