AI Article Synopsis
- Specific detection of pathogens is crucial for controlling infectious diseases.
- Two new neomycin analogs effectively target and kill various bacteria without harming macrophage-like cells.
- One analog, lipidated probe 2, has demonstrated antibacterial activity against methicillin-resistant Staphylococcus aureus.
Article Abstract
Specific detection of pathogens has long been recognized as a vital strategy in the control of infectious diseases. Two novel theranostic neomycin analogs exhibit efficient targeting, labelling and killing of broad spectrum bacteria while not damaging macrophage-like cells. Furthermore, lipidated probe 2 clearly showed antibacterial activity against methicillin-resistant S. aureus.
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| http://dx.doi.org/10.1039/c6cc08292k | DOI Listing |
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