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Retinochoroiditis secondary to Rickettsia typhi infection: a case report.
BMC Ophthalmol
March 2024
Ophthalmology Department, Rambam Health Care Campus, Haifa, Israel.
Background: To report a case of unusual presentation of retinochoroiditis caused by Rickettsia typhi in a patient without prior uveitis.
Case Presentation: In this case, we describe a 24-year-old male soldier with no previous eye disease, who was referred to our ophthalmology department due to bilateral retinochoroiditis and vitritis. The patient initially presented with a paracentral scotoma in his right eye persisting for 7 days and scattered dark spots in his left eye for 2 days in June 2023.
Long-term follow-up of a healthy man with endogenous Streptococcus anginosus endophthalmitis.
J Ophthalmic Inflamm Infect
February 2024
Department of Ophthalmology, Hadassah Medical Center, Jerusalem, Israel.
We report the long-term follow-up of an immunocompetent patient who presented with slowly progressive endogenous endophthalmitis secondary to Streptococcus anginosus. A 46-year-old healthy man presented with a two-month history of right eye iritis. On examination, visual acuity was 20/60 with intraocular pressure of 6 mm Hg.
View Article and Find Full Text PDFKnowledge and Perceptions of Reactive Arthritis Diagnosis and Management Among Healthcare Workers During the COVID-19 Pandemic: Online Survey.
J Korean Med Sci
December 2022
Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Article Synopsis
- Reactive arthritis (ReA) gained attention during the COVID-19 pandemic, but there's confusion about its link to coronavirus infections and no established treatment guidelines.* -
- An e-survey with 193 responses from 24 countries revealed that many clinicians lack a clear understanding of ReA, including its classical definition and diagnostic criteria.* -
- Results highlighted the need for updated definitions and consensus guidelines for managing ReA, particularly regarding the use of biological treatments.*
Systemic prime exacerbates the ocular immune response to heat-killed Mycobacterium tuberculosis.
Exp Eye Res
October 2022
University of Washington, Department of Ophthalmology, Seattle, WA, 98104, USA; University of Washington, Department of Biological Structure, Seattle, WA, 98195, USA; University of Washington, Department of Laboratory Medicine and Pathology, Seattle, WA, 98195, USA; University of Washington, Roger and Angie Karalis Johnson Retina Center, Seattle, WA, 98109, USA.
Post-infectious uveitis describes the condition of chronic immune mediated ocular inflammation associated with pathogens such as Mycobacterium tuberculosis (Mtb). Mtb associated post-infectious uveitis can be modeled in mice by intravitreal injection of heat-killed Mtb (HKMtb). To better understand how prior systemic exposure to the pathogen alters the local immune response to Mtb, we used flow cytometry and multiplex ELISAs to compare ocular responses to intravitreal HKMtb in the presence or absence of a systemic "prime" of HKMtb.
View Article and Find Full Text PDFPrimed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis.
J Vis Exp
December 2021
Department of Ophthalmology, University of Washington;
The term 'uveitis' describes a heterogeneous set of conditions that all feature intraocular inflammation. Broadly, uveitis is defined by etiology: infection or autoimmunity. Infectious uveitis requires treatment with the appropriate antimicrobial agents, while autoimmune uveitis requires treatment with corticosteroids or other immunosuppressive agents.
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