Interactions between π-conjugated chromophores in a giant molecular spoked wheel.

Chem Commun (Camb)

Institut für Experimentelle und Angewandte Physik, Universität Regensburg, Universitätsstraße 31, 93053 Regensburg, Germany.

Published: December 2016

We discuss the intriguing photophysics of a giant molecular spoked wheel of π-conjugated arylene-alkynylene chromophores on the single-molecule level. This "molecular mesoscopic" structure, CH, shows fast switching between the 12 identical chromophores since the fluorescence is unpolarised but only one chromophore emits at a time.

Download full-text PDF

Source
http://dx.doi.org/10.1039/c6cc08396jDOI Listing

Publication Analysis

Top Keywords

giant molecular
8
molecular spoked
8
spoked wheel
8
interactions π-conjugated
4
π-conjugated chromophores
4
chromophores giant
4
wheel discuss
4
discuss intriguing
4
intriguing photophysics
4
photophysics giant
4

Similar Publications

Sputnik virophages are small double-stranded DNA (dsDNA) viruses that replicate only inside host amoebae infected with giant dsDNA viruses, mimiviruses. Sputnik infection affects mimivirus replication, but their molecular interaction remains poorly understood. Here, we performed a time-course transcriptome analysis of cells infected with Acanthamoeba polyphaga mimivirus (APMV; hereafter referred to as Sputnik cells) and those infected with both APMV and Sputnik 3 virophage (Sputnik cells).

View Article and Find Full Text PDF

Spatial transcriptomics in glomerular diseases.

Rheumatology (Oxford)

March 2025

Department of Pathology, Medical University of Vienna, Vienna, Austria.

Spatial transcriptomics enables the study of the mechanisms of disease through gene expression and pathway activity analysis in a spatial context. Originally mainly employed in oncology, the techniques developed use different methods of transcript identification, resolution (single cells vs regions), flexibility of target regions and the type of molecules that can be assessed (RNA and/or protein). Selection of regions of interest requires both knowledge of the underlying histopathological changes and limitations of the methods, like artefacts due to variation in pre-analytics, or the probes used to analyse them.

View Article and Find Full Text PDF

Highlights from the breakout session: diagnosis and classification of vasculitis.

Rheumatology (Oxford)

March 2025

Rheumatology Department, Health New Zealand, Auckland, New Zealand.

The session on 'Diagnosis and Classification of Vasculitis' featured six oral presentations covering various aspects of vasculitis diagnosis and classification. The application of the Ankara criteria for IgA vasculitis in adults was evaluated, finding that while the criteria showed good sensitivity, their specificity was insufficient, suggesting the need for refinement. A clustering approach to classifying ANCA-associated vasculitis (AAV) identified five distinct clusters, which improved prediction of disease outcomes.

View Article and Find Full Text PDF

Highlights from the breakout session: imaging in disease assessment.

Rheumatology (Oxford)

March 2025

Department of General Internal Medicine, UZ Leuven, Leuven, Belgium.

The breakout session "Imaging in Disease Assessment" featured six abstracts on imaging advancements for vasculitis. Disease extent on cranial MRI and its association with visual complications in giant cell arteritis (GCA) was evaluated, introducing the Propensity for Enhancement for GCA (P EG) score to assess inflammation. Predictors of remission and relapse in chronic periaortitis were analyzed, suggesting the potential for tailored treatment approaches.

View Article and Find Full Text PDF

Highlights from the breakout session: transcriptomic approaches to the study of systemic vasculitis.

Rheumatology (Oxford)

March 2025

Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds and NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK.

The search for targeted therapies and biomarkers for immune-mediated systemic vasculitis requires detailed understanding of molecular pathogenesis. Whilst candidate approaches have identified new opportunities for drug repurposing, they also miss novel approaches for targeting critical immunological or stromal pathways. On the other hand, bulk transcriptional profiling may fail to capture differences in cellular composition and, depending on the cell source profiled, miss important changes within inflamed vascular tissue.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!