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Syphilitic Optic Neuropathy: Re-emerging Cases Over a 2-Year Period. | LitMetric

Syphilitic Optic Neuropathy: Re-emerging Cases Over a 2-Year Period.

Neuroophthalmology

Department of Ophthalmology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Published: April 2016

AI Article Synopsis

  • 7 cases of syphilitic optic neuropathy were identified over 2 years, all involving patients newly diagnosed with HIV.
  • Most patients presented with swollen optic discs and enlarged blind spots in their visual fields.
  • Early diagnosis and proper treatment lead to a good prognosis, with improvement in visual acuity and resolution of optic disc swelling.

Article Abstract

We report 7 cases of syphilitic optic neuropathy during a 2-year period. All patients were newly diagnosed with human immunodeficiency virus (HIV) infection. Six cases (86%) initially presented with swollen optic disc either unilaterally or bilaterally. Blind spot enlargement was the most common type of visual field defect. Final visual acuity of at least 20/25 was achieved together with visual field improvement and resolution of swollen optic disc. Optic nerve involvement can be the first manifestation of syphilis and HIV co-infection. Syphilitic optic neuropathy has an excellent prognosis if the disease diagnosed promptly and treated properly.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123058PMC
http://dx.doi.org/10.3109/01658107.2015.1134586DOI Listing

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