Metal-Organic Framework as a Protective Coating for Biodiagnostic Chips.

Adv Mater

Department of Mechanical Engineering and Materials Science, Institute of Materials Science and Engineering, Washington University in St. Louis, Saint Louis, MO, 63130, USA.

Published: February 2017

Zeolitic imidazolate framework-8 (ZIF-8) grown around antibodies anchored to plasmonic nanostructures serves as a protective layer to preserve the biorecognition ability of antibodies stored at room and elevated temperatures for several days. The biofunctionality of the ZIF-8-protected biochip can be restored by a simple water-rinsing step, making it highly convenient for use in point-of-care and resource-limited settings.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369648PMC
http://dx.doi.org/10.1002/adma.201604433DOI Listing

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