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Cell-Based Assays to Study ERK Pathway/Caveolin1 Interactions. | LitMetric

Cell-Based Assays to Study ERK Pathway/Caveolin1 Interactions.

Methods Mol Biol

Integrin Signaling Laboratory, Cell Biology & Physiology Program, Cell & Developmental Biology Area, Centro Nacional de Investigaciones Cardiovasculares, Melchor Fernandez Almagro, 3, Madrid, 28029, Spain.

Published: January 2018

AI Article Synopsis

Article Abstract

Caveolin1, the main component of caveolae, plays a major role in regulating cell motility, gene expression, and cytoskeleton remodeling downstream of many membrane receptors. Here, we summarize different techniques set up to study changes in cell morphology and cell motility regulated by ERK/caveolin1 interactions during induction of epithelial mesenchymal transition (EMT) in mesothelial cells (MCs).

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Source
http://dx.doi.org/10.1007/978-1-4939-6424-6_12DOI Listing

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