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http://dx.doi.org/10.5152/dir.2016.16257 | DOI Listing |
Adv Mater
January 2025
School of Pharmacy, Key Laboratory of Smart Drug Delivery (Ministry of Education), Fudan University, Shanghai, 201203, China.
General synthesis and mechanical understanding of type I nano-photosensitizers are of great importance for hypoxia-resistant pyroptosis inducers. Herein, a simple solvothermal treatment is developed to convert non-photosensitive small molecules (hemin) into uniform carbon nanodots (HNCDs) with strong type I photodynamic activity and red fluorescence emission. These HNCDs inherit the single atomic Fe-N center of hemin while creating sp-hybridized carbon surroundings, which synergistically modulated the energy level and electron transfer for converting the type II photodynamic process to type I.
View Article and Find Full Text PDFForensic Sci Med Pathol
January 2025
Adelaide School of Biomedicine, The University of Adelaide and Forensic Science SA, Adelaide, South Australia, Australia.
Tattooing refers to the process of creating indelible designs and texts in the human skin by introducing a variety of dyes. It has found for millennia in a range of societies. The purpose of tattooing has ranged from marking individuals of significant social standing such as chieftains in Polynesia, to those who are regarded as outcasts such as prostitutes and criminals in Europe.
View Article and Find Full Text PDFChemMedChem
January 2025
Peking University, No.38 Xueyuan Rd, 100191, Beijing, CHINA.
Low cure rate and high death rate of cancers have seriously threatened human health. The combining multiple therapies is a promising strategy for cancer treatment. In this study, we construct a novel multinucleated nanocomplex loaded with carbon dots (CDs-SA@TAMn) that responds to tumor microenvironment for combined photothermal/chemodynamic cancer therapy.
View Article and Find Full Text PDFJ Med Syst
January 2025
Department of Ophthalmology, The First Affiliated Hospital of Nanyang Medical College, Nanyang, China.
With the rise of AI platforms, patients increasingly use them for information, relying on advanced language models like ChatGPT for answers and advice. However, the effectiveness of ChatGPT in educating thyroid cancer patients remains unclear. We designed 50 questions covering key areas of thyroid cancer management and generated corresponding responses under four different prompt strategies.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Respiratory and Critical Care Medicine, The First Medical Centre of Chinese PLA General Hospital, Haidian District, Beijing, China.
Moth Flame Optimization (MFO) is a swarm intelligence algorithm inspired by the nocturnal flight mode of moths, and it has been widely used in various fields due to its simple structure and high optimization efficiency. Nonetheless, a notable limitation is its susceptibility to local optimality because of the absence of a well-balanced exploitation and exploration phase. Hence, this paper introduces a novel enhanced MFO algorithm (BWEMFO) designed to improve algorithmic performance.
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