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Repurposing Licensed Drugs with Activity Against Epstein-Barr Virus for Treatment of Multiple Sclerosis: A Systematic Approach.
CNS Drugs
January 2025
School of Medicine and Dentistry, Gold Coast Campus, Griffith University, Southport, QLD, 4222, Australia.
Background: Epstein-Barr virus (EBV) is implicated as a necessary factor in the development of multiple sclerosis (MS) and may also be a driver of disease activity. Although it is not clear whether ongoing viral replication is the driver for MS pathology, MS researchers have considered the prospect of using drugs with potential efficacy against EBV in the treatment of MS. We have undertaken scientific and lived experience expert panel reviews to shortlist existing licensed therapies that could be used in later-stage clinical trials in MS.
View Article and Find Full Text PDFThe 18th International Zebrafish Conference (IZFC2024) took place from August 17 to 21, 2024, at Miyako Messe in Kyoto, Japan. This conference attracted 641 researchers from around the world along with 83 virtual participants, making it the largest gathering since the COVID-19 pandemic. The event featured two keynote lectures, three award lectures, 36 plenary talks, 90 oral presentations, and 374 poster presentations.
View Article and Find Full Text PDFThe impact of typological similarities and differences between German and Italian on the acquisition of language-specific phonetic cues in bilingual children: insights from the T-complex.
Front Hum Neurosci
December 2024
Ph.D. Program in Speech-Language-Hearing Sciences, The Graduate Center, The City University of New York Graduate Center, New York, NY, United States.
Introduction: Lateral temporal neural measures (Na and T-complex Ta and Tb) of the auditory evoked potential (AEP) index auditory/speech processing and have been observed in children and adults. While Na is already present in children under 4 years of age, Ta emerges from 4 years of age, and Tb appears even later. The T-complex has been found to be sensitive to language experience in Spanish-English and Turkish-German children and adults.
View Article and Find Full Text PDFLove as a Commitment Device : Evidence from a Cross-Cultural Study across 90 Countries.
Hum Nat
December 2024
Institute of Psychology, University of Wrocław, Wrocław, Poland.
Given the ubiquitous nature of love, numerous theories have been proposed to explain its existence. One such theory refers to love as a commitment device, suggesting that romantic love evolved to foster commitment between partners and enhance their reproductive success. In the present study, we investigated this hypothesis using a large-scale sample of 86,310 individual responses collected across 90 countries.
View Article and Find Full Text PDFBeat gestures and prosodic prominence interactively influence language comprehension.
Cognition
December 2024
Max Plank Institute for Psycholinguistics, Wundtlaan 1, 6525 XD Nijmegen, The Netherlands; Radboud University Nijmegen, Donders Institute for Brain, Cognition and Behaviour, 6525 EN Nijmegen, The Netherlands.
Face-to-face communication is not only about 'what' is said but also 'how' it is said, both in speech and bodily signals. Beat gestures are rhythmic hand movements that typically accompany prosodic prominence in conversation. Yet, it is still unclear how beat gestures influence language comprehension.
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