We have developed recombinant fragment C based rapid point of care dipstick devices to assess tetanus immunization status using plasma or whole blood. The devices demonstrated specificity of 0.90 and sensitivity of 0.90 (whole blood)/0.94 (plasma) at field sites in Bangladesh and The Gambia when compared to a commercial ELISA with the immune cut-off titer set as ≥0.1IU/mL.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292284 | PMC |
| http://dx.doi.org/10.1016/j.diagmicrobio.2016.11.011 | DOI Listing |
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