Nanotechnology, a new paradigm in atherosclerosis treatment.

Clin Investig Arterioscler

Instituto de Medicina y Biología Experimental de Cuyo, Consejo Nacional de Investigación Científica y Tecnológica (IMBECU-CONICET), Argentina; Laboratorio de Farmacología Experimental Básica y Traslacional, Área de Farmacología, Departamento de Patología, Facultad de Ciencias Médicas, Universidad Nacional de Cuyo, Mendoza, Argentina. Electronic address:

Published: September 2018

AI Article Synopsis

  • Atherosclerosis is a prevalent disease that leads to progressive damage of blood vessels, reducing blood flow and causing complications that are often only noticeable in later stages.
  • Traditional treatments are often inadequate since many damages are irreversible, prompting the need for innovative drug delivery methods and new therapeutic targets to slow down disease progression.
  • The review emphasizes the potential of nanotechnology as a modern treatment option for atherosclerosis, while also cautioning about possible complications associated with its use.

Article Abstract

Atherosclerosis, a known and prevalent disease, causes progressive deterioration of affected vessels, inducing a blood flow reduction with different complications, and its symptoms usually manifest in advanced stages of the disease. Therefore, the classic therapeutic alternatives are insufficient because the damages are many times irreversible. For this reason, there is a need to implement intelligent forms of drug administration and develop new therapeutic targets that reduce the progression of atherosclerotic lesion. The implementation of new tools for prevention, diagnosis and treatment of this cardiovascular disease is of special interest, focusing our attention on achieving a more effective control of the immune system. Finally, this review highlights the latest knowledge about nanotechnology as a powerful, modern, and promising therapeutic alternative applied to atherosclerotic disease, as well as warning of the potential complications with their use.

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Source
http://dx.doi.org/10.1016/j.arteri.2016.09.002DOI Listing

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