This study assessed the effects of a cross-circuit training intervention program on the body composition, cardiorespiratory fitness, balance, and muscular strength endurance of overweight or obese students with intellectual disability. A total of 43 students with intellectual disability (aged 13-19 years) were enrolled in this program; 28 overweight/obese students were assigned to either an obesity-control group (n=14) or obesity-exercise group (n=14), and those with normal weight were assigned to a normal weight group (n=15). The experiment was divided into three periods: pretest (involving the three groups), exercise intervention (involving only the obesity-exercise group), and post-test (involving the obesity-exercise and obesity-control groups). The test involved measuring the body composition, 1-min sit-ups, dynamic and static balance, vertical jumps, and modified Bruce treadmill protocols for measuring cardiorespiratory fitness. The exercise program involving the cross-circuit training concept was conducted nonstop with different types of exercise activities. The training program lasted 12 weeks, and it was executed 5days a week, with each daily session lasting 50min. The results revealed that the obesity-exercise group demonstrated reduced weight, BMI, and fat mass after the intervention program. Moreover, the exercise tolerance test (including total exercise time and maximal heart rate), dynamic balance, sit-up, and vertical jump performance of the participants improved significantly. In conclusion, the cross-circuit training program effectively improved cardiorespiratory fitness, dynamic balance, muscular strength and endurance, and weight control in overweight or obese students with intellectual disability enrolled in a special education school.
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http://dx.doi.org/10.1016/j.ridd.2016.11.005 | DOI Listing |
Sci Adv
January 2025
Department of Neuroscience, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
The pathophysiology of neurodevelopmental disorders involves vulnerable neural populations, including striatal circuitry, and convergent molecular nodes, including chromatin regulation and synapse function. Despite this, how epigenetic regulation regulates striatal development is understudied. Recurrent de novo mutations in are associated with intellectual disability and autism.
View Article and Find Full Text PDFJ Intellect Dev Disabil
January 2025
Tel-Hai College, Upper Galilee, Israel.
Background: The birth of a child with an intellectual or developmental disability inherently presents challenges to parents regarding the child's long-term future. This qualitative study examined the perceptions of parents who are kibbutz members, focusing on the non-profit organisation they established and the socioeconomic model they developed to ensure the future wellbeing of their children with intellectual and developmental disabilities.
Method: In-depth interviews were conducted with 12 participants and used a thematic analysis based on case study methodology.
Subcell Biochem
January 2025
Facultad de Medicina y Ciencia, Universidad San Sebastián, Santiago, Chile.
The brain plays a vital role in maintaining homeostasis and effective interaction with the environment, shaped by genetic and environmental factors throughout neurodevelopment and maturity. While genetic components dictate initial neurodevelopment stages, epigenetics-specifically neuroepigenetics-modulates gene expression in response to environmental influences, allowing for brain adaptability and plasticity. This interplay is particularly evident in neuropathologies like Rett syndrome and CDKL5 deficiency syndrome, where disruptions in neuroepigenetic processes underline significant cognitive and motor impairments.
View Article and Find Full Text PDFIntroduction Young children with intellectual and developmental disabilities (IDD) who have limited speech and language require access to augmentative and alternative communication (AAC) intervention, including technology and instruction. While research shows that AAC intervention can effectively support communication from children with IDD, research on its impact on school readiness skills is limited. Methods Two preschool aged children with IDD participated in this study.
View Article and Find Full Text PDFBMJ Open
January 2025
IRCCS Mondino Foundation, Pavia, Italy
Introduction: Children with septo-optic-pituitary dysplasia (SOD) may experience a range of visual impairments and hormonal dysfunctions beyond developmental delay/intellectual disability. The literature describes sleep fragmentation, circadian rhythm disruptions and reduced sleep efficiency. These manifestations are believed to be closely linked to both structural and functional abnormalities associated with SOD, potentially disrupting the natural circadian rhythm.
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