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Simple and sensitive monitoring of polycyclic aromatic hydrocarbons in edible oils by polydimethylsiloxane/pyrazine-based hyper-crosslinked polymer coated stir bar sorptive extraction followed by gas chromatography-mass spectrometry detection.
Anal Chim Acta
February 2025
Food Laboratory of Zhongyuan, Luohe, 462000, Henan Province, PR China.
Background: Edible oils are susceptible to contamination with polycyclic aromatic hydrocarbons (PAHs) throughout production, storage, and transportation processes due to their lipophilic nature. The necessity of quantifying PAHs present in complex oil matrices at trace levels, which bind strongly to impurities in oil matrices, poses a major challenge to the accurate quantification of these contaminants. Therefore, the development of straightforward and effective methods for the separation and enrichment of PAHs in oil samples prior to instrumental analysis is paramount to guaranteeing food safety.
View Article and Find Full Text PDFSystematic application of saliency maps to explain the decisions of convolutional neural networks for glaucoma diagnosis based on disc and cup geometry.
Biomed Phys Eng Express
January 2025
Department of Ophthalmology, Hospital Universitario de Canarias, Carretera Ofra S/N, La Laguna, Santa Cruz de Tenerife, 38320, SPAIN.
This paper systematically evaluates saliency methods as explainability tools for convolutional neural networks trained to diagnose glaucoma using simplified eye fundus images that contain only disc and cup outlines. These simplified images, a methodological novelty, were used to relate features highlighted in the saliency maps to the geometrical clues that experts consider in glaucoma diagnosis. Despite their simplicity, these images retained sufficient information for accurate classification, with balanced accuracies ranging from 0.
View Article and Find Full Text PDFApplication of clinician support tools to improve wound healing outcomes and simplify treatment selection for effective exudate management.
Wounds
December 2024
Smith+Nephew, Watford, Hertfordshire, UK.
Background: Achievement of moisture balance can be a critical factor affecting time to closure of nonhealing wounds, and dry wounds can take much longer to heal than those with high exudate levels. Whether the goal of management is to donate moisture to the wound or control excessive fluid until the cause has been identified and addressed, choice of dressing and other wound management products can affect nursing resources, clinical outcomes, concordance, and quality of life for the patient.
Case Reports: The cases discussed illustrate differences in management approaches for dry and wet wounds and show how clinician support tools (eg, tissue type, infection/inflammation, moisture imbalance, epithelial edge advancement [TIME] clinical decision support tool) can facilitate treatment decisions.
[Barriers for including sufficient participants in multi-center drug research].
Tijdschr Psychiatr
January 2025
Background: The SPACe 2: STAR trial is a multicenter trial in children with an autism spectrum disorder, divided over nine centers in the Netherlands. However, it is challenging to include enough participants due to various factors, including the varying status of the disorder and willingness of parents and children.
Aim: To identify and overcome the bottlenecks for practitioners during the trial to prevent major delays.
Fracture Resistance and Initial Penetration Time of a Novel Zirconia Crown Design for Simplifying Future Endodontic Treatment: An In Vitro Study.
Dent J (Basel)
November 2024
Department of Prosthetic Dental Science, College of Dentistry, Jazan University, Jazan 45142, Saudi Arabia.
: This study aimed to investigate the fracture strength of a novel-designed Zirconia crown before and after access opening, and to evaluate the mode of fracture and the time needed for initial penetration through the crown. : This study involved the design and testing of 60 zirconia crowns, divided into three groups (20 crowns each) to compare different structural designs. Group 1 (Control) used a conventional full zirconia crown.
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