Structure determination by cryo-electron microscopy has approached atomic resolution and helped solve structures of large membrane-protein complexes that resisted crystallography. The 4.0 Å cryo-EM structure of one of the most intricate enzyme systems, the respirasome, in the mitochondrial inner membrane is reported in this issue of Cell.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240040 | PMC |
http://dx.doi.org/10.1016/j.cell.2016.11.025 | DOI Listing |
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