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A case of relapsed gAChR-positive autoimmune autonomic ganglionopathy treated by plasma exchange and mycophenolate mofetil.
Front Neurol
January 2025
Department of Neurology, The General Hospital of Western Theater Command, Chengdu, Sichuan, China.
Autoimmune autonomic ganglionopathy (AAG) is a rare and acquired immune-mediated disease that leads to wide autonomic failure, mainly characterized by orthostatic hypotension, gastrointestinal dysfunction, anhidrosis and poorly reactive pupils. This disorder is usually associated with autoantibodies to the ganglionic nicotinic acetylcholine receptor (gAChR-Ab). In this study, we describe a case of a gAChR-Ab-positive AAG patient with two therapeutic stages.
View Article and Find Full Text PDFEfficacy of Neuro-muscular Electrical Stimulation for Orthostatic Hypotension Associated with Long-term Disuse and Diabetic Autonomic Neuropathy: A Case Report.
Phys Ther Res
August 2024
Department of Internal Medicine, Sanseikai Kitano Hospital, Japan.
Unlabelled: Patient Background: A 75-year-old man had difficulty moving around at home because of loss of appetite and neglect of medication for several days. He was brought to the emergency room and admitted on the same day with a diagnosis of dehydration and diabetic ketoacidosis. He started physical therapy (PT), had frequent fainting and presyncope due to hypotension, and had difficulty leaving bed.
View Article and Find Full Text PDFAssociation Between Early Mobilization and Postoperative Pneumonia Following Robot-assisted Minimally Invasive Esophagectomy in Patients with Thoracic Esophageal Squamous Cell Carcinoma.
Phys Ther Res
September 2024
Division of Physical Medicine and Rehabilitation, Okayama University Hospital, Japan.
Objective: The objective of this study was to confirm that early mobilization (EM) could reduce pneumonia in patients undergoing robot-assisted minimally invasive esophagectomy (RAMIE) for thoracic esophageal squamous cell carcinoma (TESCC).
Methods: Postoperative pneumonia was defined as physician-diagnosed pneumonia using the Esophagectomy Complications Consensus Group definition of pneumonia with a Clavien-Dindo classification grade II-V on postoperative day (POD) 3-5. EM was defined as achieving an ICU Mobility Scale (IMS) ≥7 by POD 2.
Neurogenic Orthostatic Hypotension in Parkinson Disease-A Narrative Review of Diagnosis and Management.
J Clin Med
January 2025
Department of Medical Specialities I, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iași, Romania.
Neurogenic orthostatic hypotension (NOH) is a significant non-motor manifestation of Parkinson's disease (PD), that substantially affects patient disability and has a powerful impact on the quality of life of PD patients, while also contributing to increased healthcare costs. This narrative review aims to summarize key insights into the diagnosis and management of NOH in individuals with PD. For diagnosing NOH, a recently introduced and valuable metric is the ΔHr/ΔSBP index.
View Article and Find Full Text PDF[Dizziness in old age].
Z Gerontol Geriatr
January 2025
Medizinisch-Geriatrische Klinik, AGAPLESION MARKUS KRANKENHAUS, Wilhelm-Epstein-Straße 4, 60431, Frankfurt, Deutschland.
Dizziness is a frequent and often multifactorial symptom in older patients that can significantly impair the quality of life. The causes are diverse and differ from younger patients. Polyneuropathy, orthostatic dysregulation, drug-related causes, positional vertigo and bilateral vestibulopathy are more frequent in old age.
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