AI Article Synopsis

  • - A 62-year-old man was diagnosed with esophageal squamous cell carcinoma showing early invasive characteristics and lymphatic involvement after a surgical examination.
  • - He underwent surgery to remove part of his esophagus and received subsequent treatments, including chemotherapy and radiation, which initially reduced his lymph node metastases.
  • - However, after several years, the cancer recurred in the left adrenal gland, leading to further surgery and ultimately the patient's death due to cancer progression.

Article Abstract

Background: Pathological examination after endoscopic submucosal dissection revealed that a 62-year-old male had esophageal squamous cell carcinoma with lamina propria mucosal invasion and lymphatic permeation.

Case Presentation: The patient underwent subtotal esophagectomy and reconstruction as an additional therapy. At 3 years and 4 months after esophagectomy, enlargement of abdominal para-aortic lymph nodes metastases was detected by computed tomography scanning. A total of 50.4 Gy of radiation and two cycles of 5-fluorouracil plus cisplatin were administered. The lymph node metastases were markedly reduced by chemoradiotherapy; however, at 1 year and 1 month later (4 years and 5 months after esophagectomy), left adrenal gland recurrence was found. Although resection was performed, the patient died from cancer progression at 5 years and 4 months after esophagectomy.

Conclusions: This case demonstrates that esophageal squamous cell carcinoma with invasion to the lamina propria and lymphatic permeation has the potential to cause distant metastases.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127916PMC
http://dx.doi.org/10.1186/s40792-016-0271-1DOI Listing

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