CuI-Catalyzed intramolecular aminocyanation of terminal alkynes in N-(2-ethynylphenyl)-N-sulfonylcyanamides was initiated by the formation of Cu-acetylide to trigger N-CN bond cleavage of the N-sulfonylcyanamide moiety followed by CN migration to form a β-cyano Cu-vinylidene intermediate. Subsequently, the indole ring closure furnished the corresponding 1-sulfonyl-3-cyanoindoles.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c6cc08601b | DOI Listing |
Publication Analysis
Top Keywords
cui-catalyzed intramolecular
8
intramolecular aminocyanation
8
aminocyanation terminal
8
terminal alkynes
8
alkynes n-2-ethynylphenyl-n-sulfonylcyanamides
8
n-2-ethynylphenyl-n-sulfonylcyanamides cu-vinylidene
4
cu-vinylidene intermediates
4
intermediates cui-catalyzed
4
n-2-ethynylphenyl-n-sulfonylcyanamides initiated
4
initiated formation
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!