Differentiating Familial Neuropathies from Guillain-Barré Syndrome.

Pediatr Clin North Am

Department of Child and Adolescent Neurology, Medical College of Wisconsin, Milwaukee, WI, USA.

Published: February 2017

Differentiating Guillain-Barré syndrome (GBS) from inherited neuropathies and other acquired peripheral neuropathies requires understanding the atypical presentations of GBS and its variant forms, as well as historical and physical features suggestive of inherited neuropathies. GBS is typically characterized by the acute onset of ascending flaccid paralysis, areflexia, and dysesthesia secondary to peripheral nerve fiber demyelination. The disorder usually arises following a benign gastrointestinal or respiratory illness, is monophasic, reaches a nadir with several weeks, and responds to immunomodulatory therapy. Inherited neuropathies with onset before adulthood, whose presentation may mimic Guillain-Barré syndrome, are reviewed.

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Source
http://dx.doi.org/10.1016/j.pcl.2016.08.015DOI Listing

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