Scintillation imaging of tritium radioactivity distribution during tritiated thymidine uptake by PC12 cells using a melt-on scintillator.

Appl Radiat Isot

Graduate School of Pharmaceutical Sciences, Tokushima University, 1-78 Shomachi, Tokushima 770-8505, Japan; Institute for Genome Research, Tokushima University, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan.

Published: February 2017

A scintillation image of tritium fixed in a melt-on scintillator was obtained using a charged-coupled device (CCD) imager, and a linear relationship was observed between the intensity of the scintillation image and the radioactivity of tritium. In a [H]thymidine uptake experiment, a linear correlation between the intensity of the CCD image and the dilution ratio of cells was confirmed. Scintillation imaging has the potential for use in direct observation of tritium radioactivity distribution.

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http://dx.doi.org/10.1016/j.apradiso.2016.11.003DOI Listing

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