AI Article Synopsis
- A novel technique for creating 3-arylindoles utilizes visible light with dual gold and photoredox catalysts.
- This method boasts benefits like cascade catalysis, high efficiency, redox-neutral conditions, and the ability to tolerate various functional groups.
- The process involves forming an electrophilic arylgold(iii) intermediate through photoredox promotion, which then couples with an arylamine nucleophile.
Article Abstract
A new method for the synthesis of 3-arylindoles has been developed by visible light mediated dual gold/photoredox catalysis. This transformation has many features such as cascade catalysis, high efficiency, redox-neutral reaction conditions and good functional group tolerance. The reaction proceeds through the photoredox-promoted formation of an electrophilic arylgold(iii) intermediate that undergoes coupling with the arylamine nucleophile.
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| http://dx.doi.org/10.1039/c6cc08478h | DOI Listing |
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